Results 81 to 90 of about 815,018 (356)

Fat Free Mass and Fat Free Mass Index as Reference Variables for Expiratory and Inspiratory Flow Rates [PDF]

IOSR Journal of Pharmacy (IOSRPHR), 2013
Flow rates are very important factors which affect the volume and speed at which air is moved into and out of lung. Body Mass Index and Waist Hip ratio are the most commonly used parameters nowadays to assess obesity and the diseases associated with it. But both the parameters have the limitation of not distinguishing between fat compartment and muscle
openaire   +1 more source

Reference values of fat mass index and fat-free mass index in healthy Spanish adolescents. [PDF]

Nutrición Hospitalaria, 2019
Abstract Background . Body mass index (BMI) does not allow to discriminate the composition of the different body compartments. The aim of this study is to elaborate reference values ​of the fat mass index (FMI) and fat-free mass index (FFMI) in healthy adolescents using anthropometric techniques in order to be available as reference standards ...
Teodoro Durá-Travé, Fidel Gallinas-Victoriano, María Chueca-Guindulain, Sara Berrade-Zubiri, María Malumbres-Chacón, Paula Moreno-González   +5 more
openaire   +6 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Population Pharmacokinetic Modeling To Estimate the Contributions of Genetic and Nongenetic Factors to Efavirenz Disposition [PDF]

, 2016
Efavirenz pharmacokinetics is characterized by large between-subject variability, which determines both therapeutic response and adverse effects.
Bies, Robert R., Desta, Zeruesenay, Lu, Jessica, Metzger, Ingrid F., Robarge, Jason D., Skaar, Todd C., Thong, Nancy   +6 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Sedentary Behavior Is Independently Related to Fat Mass among Children and Adolescents in South China [PDF]

, 2016
We aim to explore the independent associations of sedentary behaviors (SB) with body mass distribution among Chinese children. Data on the screen-based sedentary time (television viewing and computer use) and doing homework, physical activities and ...
Cheng, Guo, Duan, Ruonan, Libuda, Lars, Muckelbauer, Rebecca, Quan, Liming, Tian, Guo, Xue, Hongmei, Yang, Min, Zhao, Li   +8 more
core   +2 more sources

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Psychophysiological Tracking of a Female Physique Competitor Through Competition Preparation [PDF]

, 2017
International Journal of Exercise Science 10(2): 301-311, 2017. Natural physique competitions are based on subjective judgments of how a competitor appears on show day.
Kanzenbach, Todd, Pettitt, Cherie, Pettitt, Robert W, Rohrig, Brandon Jay   +3 more
core   +1 more source

Serum 25-Hydroxyvitamin D and Intact Parathyroid Hormone Influence Muscle Outcomes in Children and Adolescents [PDF]

, 2018
Increases in 25-hydroxyvitamin D concentrations are shown to improve strength in adults; however, data in pediatric populations are scant and equivocal. In this ancillary study of a larger-scale, multi-sited, double-blind, randomized, placebo-controlled ...
Addison, Bergman, Bignotti, Bischoff-Ferrari, Boland, Buford, Cangussu, Carrillo, Ceglia, Ceglia, Close, DeLuca, Dhesi, El-Hajj Fuleihan, El-Hajj Fuleihan, Foo, Gerdhem, Gilsanz, Girgis, Glendenning, Goodpaster, Goran, Goswami, Gupta, Hansen, Haroon, Hassan-Smith, Hoaglin, Houston, Keihan Rodrigues Matsudo, Kwon, Lewis, Looker, Malina, Mansbach, Michael, Miljkovic-Gacic, Molenaar, Neinstein, Passeri, Pate, Pollock, Redzic, Rittweger, Rogol, Sinha, Swinford, Tanner, Templeton, Visser, Ward, Ward, Warden, Wind, Wolff, Yin   +55 more
core   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source