Results 171 to 180 of about 1,171,043 (349)

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray   +2 more
wiley   +1 more source

Radiation‐Resistant Bacteria Deinococcus radiodurans‐Derived Extracellular Vesicles as Potential Radioprotectors

open access: yesAdvanced Healthcare Materials, EarlyView.
Deinococcus radiodurans‐derived extracellular vesicles (R1‐EVs) provide radioprotection against total‐body irradiation‐induced acute radiation syndrome in mice. R1‐EVs mitigate oxidative damage by scavenging free radicals, promoting intestinal repair, enhancing hematopoietic function, and modulating immune responses. This study highlights the potential
Jeong Moo Han   +7 more
wiley   +1 more source

Egg Introduction during Infancy is Associated with Lower Fat Mass Index in Females at Early Adolescence. [PDF]

open access: yesJ Nutr, 2023
Choudhary D   +6 more
europepmc   +1 more source

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo   +11 more
wiley   +1 more source

Optimal cut-off points of fat mass index and visceral adiposity index associated with type 2 diabetes mellitus. [PDF]

open access: yesFood Sci Nutr, 2022
Bagheri A   +6 more
europepmc   +1 more source

Overweight and obesity in a Swiss city: 10-year trends [PDF]

open access: yes, 2017
Background Increased rates of overweight/obesity have been reported in recent years in developed countries. This population study of healthy subjects evaluated the changes in overweight/obesity prevalence in 2003, compared with 1993, and determined the ...
Genton, Laurence   +3 more
core  

Reinforced Polymer–Nanoparticle Hydrogels for Subcutaneous and Sustained Delivery of Trastuzumab

open access: yesAdvanced Healthcare Materials, EarlyView.
Biologic therapy development is rapidly accelerating, requiring extended delivery formulation strategies. Supramolecular hydrogels and electrostatic complexation create subcutaneous depots that release clinically relevant trastuzumab doses in a controlled manner through simple component mixing without chemical modifications.
Giovanni Bovone   +17 more
wiley   +1 more source

Non-melancholic depressive symptoms are associated with above average fat mass index in the Helsinki birth cohort study. [PDF]

open access: yesSci Rep, 2022
Eriksson MD   +9 more
europepmc   +1 more source

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