Results 61 to 70 of about 690,759 (293)
Influence of leptin on arterial distensibility - A novel link between obesity and cardiovascular disease? [PDF]
, 2002 Background-The mechanisms by which obesity increases the risk of atherosclerotic cardiovascular disease (CVD) are poorly understood. In experimental models, leptin, a hormone produced by adipose tissue, has been shown adversely to affect vascular health.
Cole, TJ +7 more
core +1 more source
Prevalence of low fat-free mass index and high and very high body fat mass index following lung transplantation [PDF]
Acta Diabetologica, 2003 The aim of this study was to determine the prevalence of low fat-free mass index (FFMI) and high and very high body fat mass index (BFMI) after lung transplantation (LTR). A total of 37 LTR patients were assessed prior to and at 1 month, 1 year and 2 years for FFM and compared to 37 matched volunteers (VOL).
Kyle, U. +4 more
openaire +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Ketogenic diet-induced weight loss is associated with an increase in vitamin d levels in obese adults [PDF]
, 2019 Vitamin D is an important micronutrient involved in several processes. Evidence has shown a strong association between hypovitaminosis D and cardio-metabolic diseases, including obesity.
Gigliotti, S +9 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Obesity is underestimated using body mass index and waist-hip ratio in long-term adult survivors of childhood cancer [PDF]
, 2012 Objective: Obesity, represented by high body mass index (BMI), is a major complication after treatment for childhood cancer. However, it has been shown that high total fat percentage and low lean body mass are more reliable predictors of ...
Blijdorp, K. (Karin) +6 more
core +4 more sources
Annals of Human Biology, 2011 Body mass index (BMI) is widely used to assess the prevalence of childhood obesity in populations and its relationship with blood pressure has been observed. However, no studies on the distribution of fat mass index (FMI) and fat-free mass index (FFMI) and their relationship with blood pressure have been reported.The present study examined the ...
Ying-Xiu, Zhang, Shu-Rong, Wang
openaire +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Genetics of fat storage in flies and worms: what went wrong? [PDF]
, 2011 Body weight and fat storage are strongly influenced by an individual’s genetic makeup. In humans, genetic polymorphisms have been identified that have effects on body mass index (BMI) and fat content (Meyre et al., 2009; Speliotes et al., 2010; Choquet ...
Al-Anzi, Bader, Zinn, Kai
core +3 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source