Results 81 to 90 of about 690,759 (293)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Tri-Ponderal Mass Index vs Body Mass Index in Estimating Body Fat During Adolescence

JAMA Pediatrics, 2017
Body mass index (BMI) is used to diagnose obesity in adolescents worldwide, despite evidence that weight does not scale with height squared in adolescents. To account for this, health care providers diagnose obesity using BMI percentiles for each age (BMI z scores), but this does not ensure that BMI is accurate in adolescents.To compare the accuracy of
Peterson, Courtney M, Su, Haiyan, Thomas, Diana M, Heo, Moonseong, Golnabi, Amir H, Pietrobelli, Angelo, Heymsfield, Steven B.   +6 more
openaire   +3 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Morphological model of the population of working-age women in Belgrade measured using electrical multichannel bioimpedance model: Pilot study [PDF]

Fizička Kultura, 2013
The aim of this study was to define the actual model of body composition status of working age women in the territory of Belgrade. The sample comprised 109 women respondents, of an average age of 35.2±9.5 and the length of service = 9.6±9.3 years.
Đorđević-Nikić Marina, Dopsaj Milivoj, Rakić Slađana, Subošić Dane, Prebeg Goran, Macura Marija, Mlađan Dragan, Kekić Dalibor   +7 more
doaj   +1 more source

Body mass index and fat free mass index in obstructive lung disease in Korea

The International Journal of Tuberculosis and Lung Disease, 2014
To investigate the relationship between body mass index (BMI), fat free mass index (FFMI) and obstructive lung disease in Korea.Based on a large population-based, nationwide survey conducted in Korea, 822 subjects with airway obstruction and the same number of healthy control subjects were selected.
S B, Kim, Y A, Kang, J Y, Jung, M S, Park, Y S, Kim, S K, Kim, J, Chang, E Y, Kim   +7 more
openaire   +3 more sources

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Anthropometric Parameters in Celiac Disease: A Review on the Different Evaluation Methods and Disease Effects [PDF]

, 2019
Artigo completo publicado em periódicoThis review compiled anthropometric data from 29 original articles, published between 1995 and 2015, corresponding to a total sample of 6368 celiac disease subjects.
Brito, Gleisson Alisson Pereira de, Costa, Allysson   +1 more
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Physical fitness in preschool children in relation to later body composition at first grade in school.

PLoS ONE, 2021
BackgroundThis study aimed to investigate whether better physical fitness in kindergarten predicts later healthier body composition in first grade at school.MethodsBody composition was assessed by skinfold thickness measurements.
Kirkke Reisberg, Eva-Maria Riso, Jaak Jürimäe   +2 more
doaj   +1 more source

Effect of body composition methodology on heritability estimation of body fatness [PDF]

, 2012
Heritability estimates of human body fatness vary widely and the contribution of body composition methodology to this variability is unknown. The effect of body composition methodology on estimations of genetic and environmental contributions to body ...
Bouchard, Thomas J., Das, Sai Krupa, Dawson-Hughes, Bess, Elder, Sonya J., Fuss, Paul J., Greenberg, Andrew S., Heymsfield, Steven B., McCrory, Megan A., Neale, Michael C., Pittas, Anastassios G., Roberts, Susan B., Saltzman, Edward   +11 more
core   +1 more source