Results 171 to 180 of about 18,252 (293)

Fat-tailed Balbas Sheep of the South-Eastern Part of Azerbaijan and the Quality of Tail Fat

Bulletin of Science and Practice
In the Republic of Azerbaijan and in particular in the Nakhchivan Autonomous Republic, the transhumance system of keeping sheep has long been adopted, which requires animals with a strong constitution, hardy and well adapted to local natural and climatic conditions. These requirements are best met by the local meat - wool - milk fat-tailed Balbas breed
openaire   +1 more source

Extracellular Vesicle‐Transferred ATP‐Citrate Lyase Induces Monocyte Differentiation Toward Tumor‐Associated Macrophages and Fuels Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Hepatocellular carcinoma (HCC)‐derived extracellular vesicles (EVs) enrich the metabolic enzyme ATP‐citrate lyase (ACLY). EV‐transferred ACLY enhances palmitate biosynthesis, increases the S‐palmitoylation and stability of multiple immune checkpoint proteins, augments the cellular immunosuppressive activity, and ultimately accelerates the malignant ...
Zhijun Liu, Haihong Lai, Qing Yang, Chaoyue Zhang, Bin Jia, Qiyi Chen, Yuling Deng, Fen Cao, Yuyu You, Zhe Li, Dongming Kuang, Bo Li   +11 more
wiley   +1 more source

Modeling the fat tails in Asian stock markets

We test whether stock returns in the Asian markets are characterized by infinite variance or just large variance, which has an important implication for the applicability of many financial models in Asian market data.
Kittiakarasakun, Jullavut, Tse, Yiuman
core  

"Leverage, heavy-tails and correlated jumps in stochastic volatility models" [PDF]

This paper proposes the efficient and fast Markov chain Monte Carlo estimation methods for the stochastic volatility model with leverage effects, heavy-tailed errors and jump components, and for the stochastic volatility model with correlated jumps.
Jouchi Nakajima, Yasuhiro Omori
core  

Nothing can replace polyunsaturated lipids. [PDF]

Elife
Rodriguez-Gallardo S, Harayama T.
europepmc   +1 more source

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source

Longitudinal Study: Swine Inflammation and Necrosis Syndrome in Suckling and Weaned Piglets Is Associated with Tail Length and Integrity in Slaughter Pigs. [PDF]

Animals (Basel)
Koenders-van Gog K, Wijnands T, Lechner M, Reiner G.   +3 more
europepmc   +1 more source

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

Advanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro, Anna Beekmayer‐Dhillon, Qi Wen Teo, Lewis Siu, Ming Yuan Li, Kate J. Heesom, Adán Pinto‐Fernández, Sumana Sanyal   +7 more
wiley   +1 more source

The tail risks of FX return distributions: a comparison of the returns associated with limit orders and market orders

This paper measures and compares the tail risks of limit and market orders using Extreme Value Theory. The analysis examines realised tail outcomes using the Dealing 2000-2 electronic broking system based on completed transactions rather than the more ...
Cotter, John, Dowd, Kevin
core  

Cultural evolution of beauty standards. [PDF]

Proc Natl Acad Sci U S A
Boucherie L, Kumar S, Ledebur K, Lohse A, Śliwa K.   +4 more
europepmc   +1 more source