An updated meta-analysis of fatal adverse events caused by bevacizumab therapy in cancer patients. [PDF]
PLoS ONE, 2014 BackgroundThe risk of fatal adverse events (FAEs) due to bevacizumab-based chemotherapy has not been well described; we carried out an updated meta-analysis regarding this issue.MethodsAn electronic search of Medline, Embase and The Cochrane Central ...
Hongxin Huang +5 more
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Incidence and risk of fatal adverse events in cancer patients treated with HER2-targeted antibody-drug conjugates: a systematic review and meta-analysis of randomized controlled trials [PDF]
BMC Cancer, 2023 Objective Antibody-drug conjugates (ADCs) that target human epidermal growth factor receptor 2 (HER2) are leading a new era of targeted cancer therapy.
Zhiwen Fu +6 more
doaj +2 more sources
Meta-analysis of incidence and risk of severe adverse events and fatal adverse events with crizotinib monotherapy in patients with ALK-positive NSCLC [PDF]
Oncotarget, 2017 Numerous clinical trials show crizotinib has promising efficacy for anaplastic lymphoma kinase (ALK) positive non-small cell lung cancer (NSCLC) patients which trigger the substitution of traditional chemotherapy to be the current standard first-line treatment for these patients.
Zhu, Qian +6 more
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PharmacoepidemiologyBackground: While adverse drug events (ADEs) are a major public health concern, data on the occurrence of lethal or fatal ADEs in Japan are limited. Therefore, this study aimed to elucidate the characteristics and reporting trends of lethal or fatal ADEs
Hiroyuki Tanaka, Toshihiro Ishii
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Fatal adverse events with molecular targeted agents in the treatment of advanced hepatocellular carcinoma: a meta-analysis of randomized controlled trials [PDF]
Drug Design, Development and Therapy, 2018 Xiaofei Li,1 Jia Wan,2 Zhenping Wu,3 Juncai Tu,1 Yongtao Hu,1 Shuang Wu,1 Lianqing Lou1 1Department of Infectious Diseases, Yiwu Central Hospital, Yiwu, China; 2The First Hospital of Nanchang, Nanchang, China; 3Gastroenterology Department, Jinhua ...
Li X +6 more
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Risk and incidence of fatal adverse events associated with immune checkpoint inhibitors: a systematic review and meta-analysis [PDF]
Therapeutics and Clinical Risk Management, 2019 Yi Jiang,1 Ning Zhang,1 Hailin Pang,1 Xiaobo Gao,2 Helong Zhang1,3 1Department of Oncology, Tangdu Hospital, Air Force Military Medical University, Xi’an, Shan’xi, China; 2Department of Medicine, Tangdu Hospital, Air Force Military Medical ...
Jiang Y, Zhang N, Pang H, Gao X, Zhang H
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Correction: Fatal adverse events associated with programmed cell death ligand 1 inhibitors: a systematic review and meta-analysis [PDF]
Frontiers in PharmacologyXuewen Wang +6 more
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Adverse cardiovascular events in patients treated with mogamulizumab
American Heart Journal Plus, 2021 Study objectives: Mogamulizumab is an important treatment for T-cell leukemia and lymphoma. Adverse cardiovascular events (ACE) after mogamulizumab therapy have not been investigated.
Jennifer M. Kwan +6 more
doaj +1 more source
BMJ Medicine, 2023 Objective To determine whether long weekly work hours and shifts of extended duration (≥24 hours) are associated with adverse patient and physician safety outcomes in more senior resident physicians (postgraduate year 2 and above; PGY2+).Design ...
Christopher P Landrigan +5 more
doaj +1 more source
Fatal Events Associated with Adverse Drug Reactions in the Korean National Pharmacovigilance Database [PDF]
Journal of Personalized Medicine, 2021 Adverse drug reactions (ADRs) pose a global public health threat, substantially contributing to death. Due to the relative paucity of clinical evidence regarding fatal ADRs, this study was performed to characterize the epidemiology of fatal ADRs in Korea.
Hyeong-Geun Jo +7 more
openaire +2 more sources