Results 51 to 60 of about 113,942 (235)

A Self‐Healing Permanent Magnet Putty for Soft Robot Skins With Force Sensing and Functional Recovery

Advanced Robotics Research, EarlyView.
Permanent magnet putty (PMP) integrates high‐coercivity NdFeB particles with a dynamic polyborosiloxane–Ecoflex matrix, achieving rapid self‐healing (90% mechanical recovery in 10 s) and magnetic recovery within 20 min. With twice the sensitivity of commercial putties, PMP enables precise 5–30 N force detection and discrimination between pressing and ...
Ruotong Zhao, Mitsuhiro Kamezaki, Ryosuke Dobashi, Yuhiro Iwamoto, Yasushi Ido, Yoshihiro Kawahara   +5 more
wiley   +1 more source

Strong cardiovascular prognostic implication of quantitative left atrial contractile function assessed by cardiac magnetic resonance imaging in patients with chronic hypertension

Journal of Cardiovascular Magnetic Resonance, 2011
Background Progressive left ventricular (LV) diastolic dysfunction due to hypertension (HTN) alters left atrial (LA) contractile function in a predictable manner.
Tsang Sui, Khin Maung, Jerosch-Herold Michael, Steel Kevin, Kaminski Matthew, Hauser Thomas, Kwong Raymond Y   +6 more
doaj   +1 more source

Immune checkpoint inhibitor-induced aplastic anaemia: Case series and large-scale pharmacovigilance analysis

Frontiers in Pharmacology, 2023
Introduction: Impressive advances in immunotherapy especially immune checkpoint inhibitors have made great progress in treating multiple cancers but can also cause serious even incurable immune-related adverse events, mostly found in colitis, dermatitis,
Qian Guo, Qian Guo, Jin Ning Zhao, Ting Liu, Jian Gao, Hui Guo, Jing Min Cheng   +6 more
doaj   +1 more source

Fatal and non-fatal adverse events of glucocorticoid therapy for Graves' orbitopathy: a questionnaire survey among members of the European Thyroid Association [PDF]

European Journal of Endocrinology, 2012
ObjectiveThe objective of this study was to investigate the side effects of glucocorticoid (GC) therapy observed by European thyroidologists during the treatment of Graves' orbitopathy (GO).DesignA questionnaire-based survey among members of the European Thyroid Association (ETA) who treat GO.ResultsA response was obtained from 128 ETA members of which
MARCOCCI, CLAUDIO, Watt T, Altea MA, Rasmussen AK, Feldt Rasmussen U, Orgiazzi J, Bartalena L, European Group of Graves' Orbitopathy   +7 more
openaire   +6 more sources

A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection against Pseudorabies Virus

Advanced Science, EarlyView.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun, Jianbo Liu, Shi‐Jia Xu, Meng‐Xin Wang, Hongliang Zhang, Yanhe Zhang, Zhi‐Jun Tian, Jin‐Mei Peng, Xin Yin, Tong‐Qing An, Xue‐Hui Cai, Yan‐Dong Tang   +11 more
wiley   +1 more source

Admission hyperglycemia as an independent predictor of long‐term prognosis in acute myocardial infarction patients without diabetes: A retrospective study

Journal of Diabetes Investigation, 2021
Aims/Introduction The predictive value of admission hyperglycemia in the long‐term prognosis of acute myocardial infarction patients is still controversial. We aimed to investigate this value based on the diabetes status. Materials and Methods We carried
Cai‐yan Cui, Ming‐gang Zhou, Lian‐chao Cheng, Tao Ye, Yu‐mei Zhang, Feng Zhu, Si‐yi Li, Xing‐lin Jiang, Qiang Chen, Ling‐yao Qi, Xu Chen, Si‐qi Yang, Lin Cai   +12 more
doaj   +1 more source

Pericardial Toxicities Associated With Immune Checkpoint Inhibitors: A Pharmacovigilance Analysis of the FDA Adverse Event Reporting System (FAERS) Database

Frontiers in Pharmacology, 2021
Introdution: Immune checkpoint inhibitors (ICIs) have significantly improved clinical outcomes for a wide range of cancers but can also lead to serious or fatal immune-related adverse events (irAEs).
Zhuo Ma, Jie Pei, Ximu Sun, Lihong Liu, Wenchao Lu, Qixiang Guo, Jiayou Lyu, Yuwei Liu, Yuhui Zhang, Zhixia Zhao   +9 more
doaj   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Overview of the Cardiotoxicity Induced by PD-1/PD-L1 Immune Checkpoint Inhibitor in Critical Care

Intensive Care Research, 2021
The Programmed Cell Death 1 (PD-1)/Programmed Death Ligand 1 (PD-L1) Immune Checkpoint Inhibitors (ICIs), have become a hot spot in the feld of cancer research and treatment, and bring new hope to patients with advanced tumors.
Ruiting Li, Xiaojing Zou, Huaqing Shu, You Shang   +3 more
doaj   +1 more source

Targeting GALNT7 Disrupts the TAZ O‐GalNAcylation Feedback Loop to Suppress Gallbladder Cancer Progression

Advanced Science, EarlyView.
Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu, Ming Zhang, Yunxiang Feng, Yibo Deng, Kai Zhao, Xiangyu Li, Yun Lu, Li Tian, Tao Yang, Wei Yao, Jianming Wang, Zhengdong Deng   +11 more
wiley   +1 more source