Results 61 to 70 of about 619,249 (293)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Marital Satisfaction and Father Involvement on Company X's Employees: The Role of Workplace Flexibility

Tazkiya Journal of Psychology
Father involvement has a positive impact on children's cognitive, emotional and social development. However, the level of this involvement is low in the Asian context, particularly in Indonesia, where traditional gender roles often reduce paternal ...
Siti Dara Futri Somantri, Missiliana Riasnugrahani, Tery Setiawan   +2 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

The culture of public fathers in the small city: Where does the culture of involved fathering reside in the public spaces of the small city? [PDF]

, 2011
Father Involvement research often focuses on issues relating to the impacts of paternal engagement on child development and the broader benefits of Father Involvement for fathers and their families.

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Parents' involvement in child care: do parental and work identities matter? [PDF]

, 2014
The current study draws on identity theory to explore mothers' and fathers' involvement in childcare. It examined the relationships between the salience and centrality of individuals’ parental and work-related identities and the extent to which they are ...
Bianchi S., Goldberg J. S., Hayes A. F., Jacobs J. A., Jacqueline Scott, McCall G. J., Rosenberg M., Ruth Gaunt, Stryker S., Sullivan O.   +9 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

The Impact of Paternity Leave on Long-term Father Involvement [PDF]

Using Norwegian registry data we investigate how paternity leave affects fathers’ long-term earnings. In 1993 Norway introduced a paternity quota of the paid parental leave.
Ingeborg F. Solli, Mari Rege
core   +3 more sources

Psychological Well-Being, Gender Ideology, dan Waktu sebagai Prediktor Keterlibatan Ayah

Jurnal Psikologi, 2019
This study aimed to examine the role of psychological well-being, gender ideology, time spent together with children, and time spent at work in predicting father involvement. This study was conducted on fathers with at least one child aged 0-12 years old,
Cantyo Atindriyo Dannisworo, Fadhilah Amalia   +1 more
doaj   +1 more source

PENGARUH KETERLIBATAN AYAH DALAM PROSES PENGASUHAN TERHADAP PERILAKU LEKAT(ATTACHMENT BEHAVIOR) ANAK [PDF]

, 2006
The involvement of fathers in child-rearing process is the father participation in child care daily, which includes the involvement of physically, emotionally, either directly or indirectly.
Rahmani, Cempluk Yudhagalih
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