Results 61 to 70 of about 759,619 (365)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Dyadic associations between marital satisfaction and coparenting quality: gender differences and the moderating role of caregiving identity

Frontiers in Sociology
Our study investigated the contribution of caregiving identity in the association between marital satisfaction and coparenting quality in fathers and mothers from a sample of opposite-sex couples of young children living in different areas of the United ...
Patty X. Kuo, Weiman Xu, Zhenqiao Yang
doaj   +1 more source

Father’s Perspectives on Family Relationships and Mental Health Treatment Participation in the Context of Maternal Postpartum Depression

Frontiers in Psychology, 2021
Objective: To understand the perspectives of fathers whose partners experienced postpartum depression, particularly (1) views on how fathers and family relationships were impacted by maternal PPD, and (2) attitudes regarding inclusion of fathers within ...
Cynthia L. Battle, Cynthia L. Battle, Cynthia L. Battle, Amalia Londono Tobon, Amalia Londono Tobon, Margaret Howard, Margaret Howard, Ivan W. Miller, Ivan W. Miller   +8 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Challenging Behaviors in Young Children: The Father\u27s Role [PDF]

, 2004
In this study, the authors examined the parenting practices, developmental expectations, and stress levels of 136 fathers and the challenging and prosocial behaviors of their 1- to 5-year-old children.
Burbach, Ann D, Fox, Robert A., Nicholson, Bonnie C   +2 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Supporting Young Fathers [PDF]

, 2008
This guide explores how professionals who work with young fathers can help them to be there for their new families by first helping them to develop as individuals.

core  

This Is Not a Myeloproliferative Neoplasm…

Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Indonesian Fathers’ Perceptions of Maternal Healthcare During the Perinatal Period [PDF]

Journal of Client-centered Nursing Care
Background: In Indonesia, a developing nation characterized by a robust patriarchal culture, paternal involvement during the perinatal phase is uncommon.
Giyawati Yulilania Okinarum, Inayati Ceria   +1 more
doaj