Results 61 to 70 of about 1,993,187 (364)

Performance of Composite Endpoints Defining Progression Independent of Relapse Activity in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The characteristics and utility of composite progression independent of relapse activity (cPIRA; worsening on the Expanded Disability Status Scale [EDSS], or 9‐Hole Peg Test, or Timed 25‐Foot Walk Test) were evaluated as an endpoint in relapsing multiple sclerosis (RMS) trials using the ENSEMBLE (NCT03085810) and pooled OPERA I/II ...
Ludwig Kappos   +11 more
wiley   +1 more source

Investigating the causes and consequences of controlled rest on the flight deck

open access: yesFrontiers in Environmental Health
IntroductionFatigue is a known issue in aviation due to long and irregular working hours. In some regions, pilots are permitted to sleep during a controlled rest period on the flight deck to manage unexpected sleepiness.
Cassie J. Hilditch   +5 more
doaj   +1 more source

Fatigue crack growth in thin notched woven glass composites under tensile loading. Part II: modelling [PDF]

open access: yes, 2011
Fatigue propagation of a through-the-thickness crack in thin woven glass laminates is difficult to model when using homogeneous material assumption. Crack growth depends on both the fatigue behaviour of the fibres and of the matrix, these two phenomena ...
Barrau, Jean-Jacques   +3 more
core   +3 more sources

Continuous Monitoring of Bladder Dysfunction in People With Multiple Sclerosis: Wearables for the Bladder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Bladder dysfunction affects over 85% of people with multiple sclerosis (PwMS), yet current assessment methods are limited to periodic in‐clinic evaluations or subjective patient reports, failing to capture real‐world symptom fluctuations.
Valerie J. Block   +8 more
wiley   +1 more source

Glial Activation and Expression of the Serotonin Transporter in Chronic Fatigue Syndrome

open access: yesFrontiers in Psychiatry, 2018
Fatigue is commonly reported in a variety of illnesses and has major impact on quality of life. Chronic fatigue syndrome (CFS) is a debilitating syndrome of unknown etiology. The clinical symptoms include problems in neuroendocrine, autonomic, and immune
Mami Noda   +3 more
doaj   +1 more source

Unipolar and bipolar fatigue in antiferroelectric lead zirconate thin films and evidences for switching-induced charge injection inducing fatigue

open access: yes, 2010
For the first time, we show that unipolar fatigue does occur in antiferroelectric capacitors, confirming the predictions of a previous work [Appl. Phys. Lett., 94, 072901 (2009)].
Lou, X. J., Wang, J.
core   +1 more source

High cycle fatigue of ARMCO iron severely deformed by ECAP [PDF]

open access: yes, 2017
The high-cycle fatigue behavior of ARMCO iron severely deformed by Equal Channel Angular Pressing (ECAP) at room temperature through route Bc until 8 passes, with an average grain size of ~365 nm, was studied and compared with the same material in the ...
Cabrera Marrero, José M.   +2 more
core   +2 more sources

Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova   +5 more
wiley   +1 more source

Early pubertal timing is a risk factor for adolescent dysmenorrhea

open access: yesnpj Women's Health
Females who experience menarche early have elevated risk for dysmenorrhea; yet, other puberty features precede menarche. Using data from the Adolescent Brain Cognitive Development Study®, pubertal timing was estimated via random effects linear growth ...
Christel M. Portengen   +8 more
doaj   +1 more source

Performance of an Ambulatory Dry-EEG Device for Auditory Closed-Loop Stimulation of Sleep Slow Oscillations in the Home Environment

open access: yesFrontiers in Human Neuroscience, 2018
Recent research has shown that auditory closed-loop stimulation can enhance sleep slow oscillations (SO) to improve N3 sleep quality and cognition. Previous studies have been conducted in lab environments.
Eden Debellemaniere   +12 more
doaj   +1 more source

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