Results 71 to 80 of about 1,365,433 (369)

Investigating the causes and consequences of controlled rest on the flight deck

Frontiers in Environmental Health
IntroductionFatigue is a known issue in aviation due to long and irregular working hours. In some regions, pilots are permitted to sleep during a controlled rest period on the flight deck to manage unexpected sleepiness.
Cassie J. Hilditch, Lucia Arsintescu, Sean Pradhan, Sean Pradhan, Kevin B. Gregory, Erin E. Flynn-Evans   +5 more
doaj   +1 more source

Performance of an Ambulatory Dry-EEG Device for Auditory Closed-Loop Stimulation of Sleep Slow Oscillations in the Home Environment

Frontiers in Human Neuroscience, 2018
Recent research has shown that auditory closed-loop stimulation can enhance sleep slow oscillations (SO) to improve N3 sleep quality and cognition. Previous studies have been conducted in lab environments.
Eden Debellemaniere, Eden Debellemaniere, Eden Debellemaniere, Stanislas Chambon, Stanislas Chambon, Clemence Pinaud, Valentin Thorey, David Dehaene, Damien Léger, Mounir Chennaoui, Mounir Chennaoui, Pierrick J. Arnal, Mathieu N. Galtier   +12 more
doaj   +1 more source

Mitochondrial DNA disorders in neuromuscular diseases in diverse populations

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao, Katherine R Schon, Jana Vandrovcova, Özlem Yayıcı Köken, Sharika Raga, Kireshnee Naidu, Maryke Schoonen, Nimita Rani, Pedro Tomaselli, Dipti Baskar, Musambo Kapapa, Ipek Polat, Lindsay A Wilson, Kumarasamy Thangaraj, Uluç Yiş, Bevinahalli N Nandeesh, David Bearden, Michelle Kvalsund, Franclo Henning, Seena Vengalil, Atchayaram Nalini, Claudia F. R. Sobreira, Wilson Marques, Haluk Topoloğlu, Michael G Hanna, Sireesha Yareeda, Venugopalan Y Vishnu, Francois H van der Westhuizen, Izelle Smuts, Surita Meldau, Jo Wilmshurst, Büşranur Çavdarlı, Jeannine Heckmann, Patrick F Chinnery, Rita Horvath   +34 more
wiley   +1 more source

Glial Activation and Expression of the Serotonin Transporter in Chronic Fatigue Syndrome

Frontiers in Psychiatry, 2018
Fatigue is commonly reported in a variety of illnesses and has major impact on quality of life. Chronic fatigue syndrome (CFS) is a debilitating syndrome of unknown etiology. The clinical symptoms include problems in neuroendocrine, autonomic, and immune
Mami Noda, Masataka Ifuku, Md. Shamim Hossain, Toshihiko Katafuchi   +3 more
doaj   +1 more source

Post-buckling analysis method of stiffened composite panels and test verification

Journal of Aeronautical Materials, 2021
Post-buckling analysis methods of fiber-reinforced T section stiffened composite panels were investigated. In this paper, the Finite Element Model was presented.
LIN Guowei, LI Xinxiang
doaj   +1 more source

Liraglutide for idiopathic intracranial hypertension: a real‐world propensity score‐matched study

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Idiopathic intracranial hypertension (IIH) is a neurological disorder predominantly affecting young women with obesity, characterized by elevated intracranial pressure. While current treatments include weight loss counseling, medical therapies, and surgical interventions, their limitations necessitate exploring novel therapeutic ...
Ahmed Y. Azzam, Muhammed Amir Essibayi, Dhrumil Vaishnav, Mohammed A. Azab, Mahmoud M. Morsy, Osman Elamin, Adam Elswedy, Oday Atallah, Hana J. Abukhadijah, Adam A. Dmytriw, Amanda Baker, Deepak Khatri, Neil Haranhalli, David J. Altschul   +13 more
wiley   +1 more source

Capturing what matters: Patient‐reported LGI1‐ANTibody encephalitis outcome RatiNg scale (LANTERN)

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Background LGI1‐antibody encephalitis (LGI1‐Ab‐E) is a common form of autoimmune encephalitis where most patients demonstrate ‘good’ clinician‐rated outcomes. However, more targeted questionnaires reveal numerous debilitating symptoms for many years.
Mark J Kelly, Barbara Wagner, Bryan Ceronie, Christine Strippel, Ann Yee Lin, Adam Handel, John Soltys, Sophie Binks, Philip A Powell, Sarosh R Irani   +9 more
wiley   +1 more source

Genetics and Cognitive Vulnerability to Sleep Deprivation in Healthy Subjects: Interaction of ADORA2A, TNF-α and COMT Polymorphisms

Life, 2021
Several genetic polymorphisms differentiate between healthy individuals who are more cognitively vulnerable or resistant during total sleep deprivation (TSD).
Mégane Erblang, Catherine Drogou, Danielle Gomez-Merino, Arnaud Rabat, Mathias Guillard, Pascal Van Beers, Michael Quiquempoix, Anne Boland, Jean François Deleuze, Robert Olaso, Céline Derbois, Maxime Prost, Rodolphe Dorey, Damien Léger, Claire Thomas, Mounir Chennaoui, Fabien Sauvet   +16 more
doaj   +1 more source

Novel Phenotypes and Deep Intronic Variant Expand TH‐Associated Dopa‐Responsive Dystonia Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Approximately 20% of dopa‐responsive dystonia (DRD) cases remain genetically unresolved. Using whole‐genome sequencing, we identified two TH variants in a young DRD patient, including a novel deep intronic variant. Minigene assays confirmed that this variant causes aberrant splicing.
Xiaosheng Zheng, Chenxin Ying, Nan Jin, Jinghong Ma, Xinhua Wan, Xunhua Li, Wei Luo   +6 more
wiley   +1 more source

Protocol for a pragmatic trial of Cannabidiol (CBD) to improve chronic pain symptoms among United States Veterans

BMC Complementary Medicine and Therapies
Background Chronic pain affects over 100 million Americans, with a disproportionately high number being Veterans. Chronic pain is often difficult to treat and responds variably to medications, with many providing minimal relief or having adverse side ...
Rachel S. Bergmans, Riley Wegryn-Jones, Catherine Klida, Vivian Kurtz, Laura Thomas, David A. Williams, Daniel J. Clauw, Kelley M. Kidwell, Amy S. B. Bohnert, Kevin F. Boehnke   +9 more
doaj   +1 more source