Dissipatively Fueled Unidirectionally Communicating DNA Circuits That Control Biocatalysis
Unidirectionally communicating, out‐of‐equilibrium DNA circuits are used to control enzyme activity. Transient DNAzyme activation generates fuel for temporal trypsin activation. Cyclic fuel‐driven hybridization and exonuclease‐mediated reset enable precise control over lifetimes, which is analyzed using combined experimental and computational ...
Philippe Jung +6 more
wiley +2 more sources
Investigating Reinforcing and Cracking Resistance Behaviors of Waste Sweet Potato Vine Straw Fiber (WSVF) in Gel-like Base Asphalt. [PDF]
Fang C +8 more
europepmc +1 more source
The Clinical Spectrum and Neurodevelopmental Pathogenesis of KPTN‐Related Disorder in a Mouse Model
Objective Pathogenic variants in Kaptin (KPTN) cause KPTN‐related disorder (KRD). KPTN modulates mTOR signaling activation within the KICSTOR complex in response to cellular amino acid levels. We define the clinical spectrum and investigate the developmental pathogenesis of KRD.
Lettie E. Rawlins +104 more
wiley +1 more source
The excited‐state intramolecular proton transfer (ESIPT) photoswitch tpmSA, which features an oxygen−acceptor, exhibits higher photochromic contrast (ΔE*Lab>74) than its nitrogen‐acceptor Schiff base analogues (ΔE*Lab<30). Theoretical calculations indicate that tpmSA effectively suppresses GSIPT, thereby enhancing the contrast.
Yahui Chen +10 more
wiley +2 more sources
Despite significant advances, most academic research fails to result in medical products that benefit patients. This guide shares five key steps to help researchers close that gap: set clear goals, test thoroughly, protect ideas, build diverse teams, and partner with industry.
Cristina Oldani +4 more
wiley +1 more source
Effect of reinforcement type and viscoelasticity on static crack growth, fatigue, and creep resistance in acrylonitrile butadiene rubber (NBR) elastomers. [PDF]
Tavosi S +3 more
europepmc +1 more source
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari +5 more
wiley +1 more source
A Review of the Parameters Controlling Crack Growth in AM Steels and Its Implications for Limited-Life AM and CSAM Parts. [PDF]
Jones R +7 more
europepmc +1 more source
Effect of cutting process parameters on fatigue properties of quenched and tempered 42CrMo steel. [PDF]
Tang K +9 more
europepmc +1 more source
Numerical study on fatigue failure mechanism of reinforced concrete slabs under coupled action of corrosion and cyclic loading. [PDF]
Wang S, Zhao Q, Song P, Yang F.
europepmc +1 more source

