Results 191 to 200 of about 82,312 (308)

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong, Wenting Hui, Sai Qiao, Qifeng Ji, Miao Liu, Bangle Zhang, Daozhou Liu, Yumei Wu, Siyuan Zhou   +8 more
wiley   +1 more source

Industrial Validation and Mechanical Characterization of SMA Mixtures Stabilized with Recycled Polymeric Fibers from Waste Tires. [PDF]

Polymers (Basel)
Calabi-Floody A, Valdés-Vidal G, Mignolet-Garrido C, Díaz-Montecinos C, Fonseca-Ibarra C.   +4 more
europepmc   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source

Evaluation of Pearlite Steel Thermite Weldments' Hydrogen Degradation for Application of Additively Manufactured Crack-Resistant Material Inserts. [PDF]

Materials (Basel)
Kawiak M, Balitskii AI, Królikowski MA, Balitska VO, Dowejko JM.   +4 more
europepmc   +1 more source

High‐Throughput Data Generation and Transfer Learning Enabled Microstructure‐Property Integrated Design of Nickel‐Based Powder Metallurgy Superalloy

Advanced Science, EarlyView.
An integrated transfer learning framework integrates CALPHAD simulations, diffusion‐multiple experiments, and literature data to predict long‐term microstructural stability and short‐term mechanical properties of Ni‐based powder metallurgy superalloys. Based on these model predictions, a high‐performance, low‐density alloy, USTB‐PM750, is designed from
Zixin Li, Hongtao Zhang, Zichao Peng, Yuheng Zhang, Qian Lv, Yihuan Cao, Xuqing Wang, Huadong Fu, Jianxin Xie   +8 more
wiley   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Effect of Fiber Characteristics on Cracking Resistance Properties of Stone Mastic Asphalt (SMA) Mixture. [PDF]

Polymers (Basel)
Yang K, Huang W, Sun M, Zheng Z, Lin H.
europepmc   +1 more source

Advanced Technologies for Characterizing and Detecting Battery Thermal Failure: A Review

Advanced Science, EarlyView.
Illustration of advanced characterization techniques to predict battery thermal failure. ABSTRACT Energy storage is essential in accelerating the global transition toward clean and sustainable energy across various sectors. Lithium‐ion batteries (LIBs) have become increasingly significant for energy storage due to their high energy density, low ...
Yongxiu Chen, Zeyu Sun, Wei Zong, Yuhang Dai, Kai Ling Ng, Paul R. Shearing   +5 more
wiley   +1 more source

Rutting and Fatigue Cracking Resistance of Waste Cooking Oil Modified Trinidad Asphaltic Materials. [PDF]

ScientificWorldJournal, 2015
Maharaj R, Ramjattan-Harry V, Mohamed N.
europepmc   +1 more source

Artificial Piezoelectric Interface Enables Ultrafast Interfacial Ion Kinetic for Highly‐Sensitive Piezoionic Sensors

Advanced Science, EarlyView.
This study proposes a piezoelectric interface modification strategy to amplify the piezoionic effect. The piezoelectric interface generates an intrinsic electric field, which not only drives rapid ion migration but also concentrates polarized ions on the interface. The flexible sensor delivers superior performance, such as a quick response rate, strong
Yanyu Chen, Xingyue Ling, Rizhong Gao, Xiaohong Zhang, Xi Chen, Chao Lu   +5 more
wiley   +1 more source