Results 181 to 190 of about 48,809 (312)

Three‐dimensional geometric morphometric analysis of diaphragmatic dome motion in COPD patients

open access: yesThe Anatomical Record, EarlyView.
Abstract Diaphragmatic dysfunction is a hallmark of chronic obstructive pulmonary disease (COPD), especially in emphysema, where hyperinflation alters diaphragm geometry and impairs inspiratory mechanics. However, quantitative three‐dimensional (3D) assessments of diaphragmatic dome shape and motion across COPD phenotypes are limited.
José M. López‐Rey   +5 more
wiley   +1 more source

Efficacy and Safety of Guselkumab in Participants With Active Psoriatic Arthritis After Inadequate Response to One Prior Tumor Necrosis Factor Inhibitor: Week‐24 Results of a Phase 3, Randomized, Placebo‐Controlled Study

open access: yesArthritis &Rheumatology, EarlyView.
Objective To evaluate the efficacy and safety of guselkumab, an interleukin‐23p19 subunit inhibitor, in participants with active psoriatic arthritis (PsA) and inadequate response (inadequate efficacy and/or intolerance) to one prior tumor necrosis factor (TNF) inhibitor.
Alexis Ogdie   +12 more
wiley   +1 more source

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

open access: yesArthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola   +14 more
wiley   +1 more source

An improved law of cumulative damage in metal fatigue

open access: yes, 1961
After a brief account of theories currently put forward on damage accumulation, a modification of the best of these, the linear rule of damage accumulation, is presented. This theory is based on a new approach to the problem wherein the material behaviour in each of three different stress regions is analysed, in contrast to current approaches which ...
openaire   +1 more source

Immersive virtual reality as a teaching tool in neuroanatomy: A scoping review

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Basic core courses in various undergraduate programs, such as neuroanatomy, pose a challenge for students due to the large volume and complexity of the content. In this context, educational technologies such as immersive virtual reality (IVR), which allow students to actively interact with learning materials, offer a complementary pedagogical ...
Nathálya Gardênia de Holanda Marinho Nogueira   +7 more
wiley   +1 more source

Data, not documents: Moving beyond theories of information‐seeking behavior to advance data discovery

open access: yesJournal of the Association for Information Science and Technology, Volume 76, Issue 4, Page 649-664, April 2025.
Abstract Many theories of human information behavior (HIB) assume that information objects are in text document format. This paper argues four important HIB theories are insufficient for describing users' search strategies for data because of assumptions about the attributes of objects that users seek.
Anthony J. Million   +3 more
wiley   +1 more source

Fatigue model based on a cohesive law

open access: yes
A computational model to simulate fatigue driven crack growth with focus on reasonable computaional cost. The model will be calibrated and validated with experimental data from subtask 3.2.1. The formulation, implementation, use and validation will be described in a memo.
openaire   +1 more source

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