Results 191 to 200 of about 223,101 (311)

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Fuzzy-Modulus-Based Layered Elastic Analysis of Asphalt Pavements for Enhanced Fatigue Life Prediction. [PDF]

Materials (Basel)
Zbiciak A, Volchok D, Kozyra Z, Michalczyk R, Al Garssi N.   +4 more
europepmc   +1 more source

Experiment and Theoretical Investigation on Fatigue Life Prediction of Fracturing Pumpheads Based on a Novel Stress-Field Intensity Approach. [PDF]

Materials (Basel), 2022
Zeng Y, Li M, Wu H, Li N, Zhou Y.
europepmc   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Fatigue Life Prediction of CFRP-FBG Sensor-Reinforced RC Beams Enabled by LSTM-Based Deep Learning. [PDF]

Polymers (Basel)
Jia M, Zhou C, Pei X, Xu Z, Xu W, Wan Z.
europepmc   +1 more source

Torsional Fatigue Life Prediction of 30CrMnSiNi2A Based on Meso-Inhomogeneous Deformation. [PDF]

Materials (Basel), 2021
Cen CX, Lu DM, Qin DW, Zhang KS.
europepmc   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

High-Cycle Fatigue Life Prediction of Additive Manufacturing Inconel 718 Alloy via Machine Learning. [PDF]

Materials (Basel)
Song Z, Peng J, Zhu L, Deng C, Zhao Y, Guo Q, Zhu A.   +6 more
europepmc   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Corrosion fatigue life prediction of multiple austenitic stainless steel grades in high-temperature, high-pressure water environments using a GA-optimized neural network. [PDF]

Sci Rep
Bhardwaj HK, Shukla M.
europepmc   +1 more source