Results 81 to 90 of about 428,197 (310)
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
In order to study the fatigue performance and fatigue failure mode of the composite box girder with steel bottom plate and corrugated webs (SBCSWs), the model beam was made and the constant and variable amplitude fatigue experiment were performed ...
Shijin Wang +3 more
doaj +1 more source
Study of a fatigue load model for highway bridges in Southeast China
Although fatigue damage has become one of the main causes of structural damage to bridges, standard vehicle models for highway bridge fatigue design have not as yet been determined in China.
Yuzhao Liang, Feng Xiong
doaj +1 more source
A comparison of reliability and conventional estimation of safe fatigue life and safe inspection intervals [PDF]
Both the conventional and reliability analyses for determining safe fatigue life are predicted on a population having a specified (usually log normal) distribution of life to collapse under a fatigue test load.
Hooke, F. H.
core +1 more source
Fatigue delamination behaviour of unidirectional carbon fibre/epoxy laminates reinforced by Z-Fiber® pinnin [PDF]
-Pin reinforced carbon-fibre epoxy laminates were tested under Mode I and Mode II conditions, both quasi-statically and in fatigue. Test procedures were adapted from existing standard or pre-standard tests. Samples containing 2% and 4% areal densities
Brunner, A. J. +3 more
core +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
An improved procedure for generating standardised load-time histories for marine structures [PDF]
The load sequence effect has been proved from laboratory tests to be an influencing factor that cannot be neglected in the fatigue analysis of marine structures.
Cui, W, Li, S, Paik, JK
core +1 more source
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg +20 more
wiley +1 more source
The long-term durability performance of ballastless track systems exhibits significant dependence on their in-service environmental conditions. In addition to cyclic fatigue loading from train operations, critical durability challenges arise from the ...
Siqi Yang +8 more
doaj +1 more source
Anti-buckling assembly prevents buckling of sheet metal fatigue specimen when axial compressive load is applied. It provides for cyclic heating and cooling of specimen during testing. Assembly permits tests at two locations on specimen.
Eichenbrenner, F. E., Imig, L. A.
core +1 more source

