Results 41 to 50 of about 431,285 (310)

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim, Han Gil Seo, Roh‐Eul Yoo, Byung‐Mo Oh   +3 more
wiley   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Fatigue Risks in the Connections of Sign Support Structures [PDF]

, 2013
This research effort develops a reliability-based approach for prescribing inspection intervals for mast-arm sign support structures corresponding to user-specified levels of fatigue-induced fracture risk.
Diekfuss, Joseph A., Foley, Christopher M., Wan, Baolin   +2 more
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Research on TBM Cutterhead Crack Damage and Fatigue Reliability

Applied Sciences, 2021
The cutterhead of a tunnel-boring machine (TBM) is the main weighted part in the process of tunneling and bears loadings in different directions. A fatigue failure of a cutterhead would severely affect the construction progress and safety.
Ding Wang, Chuanyong Qu
doaj   +1 more source

Probabilistic Fatigue and Reliability Simulation

Procedia Structural Integrity, 2019
Abstract This paper demonstrates the advantages of using ‘probabilistic fatigue simulation’ and ‘stochastic’ design over the traditional ‘deterministic’ design approach. It demonstrates how ‘Monte Carlo’ simulation with ‘Latin hypercube sampling’ are effective for obtaining simulated reliability tests based on standard FEA models.
A. Halfpenny, A. Chabod, P. Czapski, J. Aldred, K. Munson, M. Bonato   +5 more
openaire   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Direct and indirect effects of mood on risk decision making in safety-critical workers [PDF]

, 2012
The study aimed to examine the direct influence of specific moods (fatigue, anxiety, happiness) on risk in safety-critical decision making. It further aimed to explore indirect effects, specifically, the potential mediating effects of information ...
Arkes, Armitage, Barling, Baron, Bless, Bodenhausen, Bodenhausen, Brown, Cohen, Conway, Derryberry, Fiona A. Jones, Forgas, Forgas, Gambetti, Goldberg, Griffin, Hockey, Hockey, Isen, Isen, Isen, James I. Morgan, Johnson, Kahn, Kahneman, Keltner, Kogan, Leith, Lerner, Lerner, Lerner, Lerner, Loewenstein, Loewenstein, Mackinnon, Maner, Mano, Martin, Mathews, Mathews, Maule, Maule, Mineka, Patterson, Peter R. Harris, Pietromonaco, Preacher, Smets, Sobel, Spielberger, Tellegen, Tiedens, Tsai, Underwood, Wiegmann, Wright, Ybema   +57 more
core   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

Fatigue Reliability Design Method for Large Aviation Planetary System Considering the Flexibility of the Ring Gear

Applied Sciences, 2022
As the foundation and core of various heavy aircraft transmission systems, the reliability level of large-scale aviation planetary mechanism restricts the economic affordability and service safety for the aircraft to a great extent.
Ming Li, Yuan Luo, Liyang Xie
doaj   +1 more source