Multiomics Insights Into AL Amyloidosis
ABSTRACT Light chain amyloidosis is a systemic or localized protein conformational disorder triggered by misfolded immunoglobulin light chains, leading to amyloid fibril deposition. The disease is characterized by multiorgan involvement and delayed diagnosis, contributing to poor prognosis and high mortality rates.
Zixuan Zhang +6 more
wiley +1 more source
Symptom profiles and health-related quality of life in Korean adults with post-acute sequelae of SARS-CoV-2 infection (PASC): A latent profile analysis. [PDF]
Kim SJ, Kim J.
europepmc +1 more source
The Hidden Burden of Hemifacial Spasm: A Systematic Review of Non‐Motor Symptoms
Abstract Background Hemifacial spasm (HFS) is a chronic neurological disorder characterized by involuntary contractions of facial muscles. Traditionally regarded as a motor condition, HFS encompasses a spectrum of non‐motor symptoms that are often overlooked but significantly affect patients’ quality of life.
Miriam Carvalho Soares +2 more
wiley +1 more source
Risk factors for severe post-COVID condition in children, adolescents, and young adults. [PDF]
Donath Q +29 more
europepmc +1 more source
High Prevalence and Clinical Impact of Fibromyalgia in Functional Motor Disorder
Abstract Background Fibromyalgia is characterized by widespread pain, fatigue, sleep and cognitive symptoms. It overlaps clinically with functional motor disorder (FMD), yet its prevalence and impact in FMD remain uncertain. Objective To determine the prevalence of fibromyalgia in FMD using the current criteria and evaluate its effects on motor ...
Tereza Serranová +6 more
wiley +1 more source
A Perspective on Observation as Intervention in Chronic Diagnostic Complexity. [PDF]
Niederman CN.
europepmc +1 more source
Living with the Unknown: Intolerance of Uncertainty in Parkinson's Disease
Abstract Background Parkinson's disease (PD) is marked by pervasive uncertainty due to fluctuating motor and non‐motor symptoms, variable treatment response, and an unpredictable clinical course. Intolerance of uncertainty (IU), a tendency to perceive ambiguity as threatening and respond with worry, avoidance, or decisional paralysis, may be ...
Bradley McDaniels +3 more
wiley +1 more source
When Dryness Extends to the Brain: Brain-Related Non-Sicca Manifestations of Sjögren's Disease. [PDF]
Kolanko M, Grabowska J, Sebastian A.
europepmc +1 more source
Abstract Background Functional movement disorder (FMD), a subtype of functional neurological disorder, is a complex neuropsychiatric syndrome characterized by inconsistent and incongruent motor symptoms. Despite its relatively high prevalence, FMD remains associated with delayed diagnosis, significant disability, and limited evidence to guide ...
Andrea Soumbasis +6 more
wiley +1 more source
Comprehensive Immunophenotyping of Monocytes and Dendritic Cells Suggests Distinct Pathophysiology in Chronic Fatigue Syndrome and Long COVID. [PDF]
Petrov S +10 more
europepmc +1 more source

