Results 51 to 60 of about 3,280,665 (275)

Current research priorities in chronic fatigue syndrome/myalgic encephalomyelitis: Disease mechanisms, a diagnostic test and specific treatments [PDF]

, 2006
Chronic fatigue syndrome (CFS) is an illness characterised by disabling fatigue of at least 6 months duration, which is accompanied by various rheumatological, infectious and neuropsychiatric symptoms.
Langford, P.R., Langford, P.R, Peveler, R. C., Hodgetts, A., Bansal, A., Smith, Andrew Paul, R Petty, Axford, J.S., Devanur, L.D., Holgate, S.T., Holgate, S.T, A Hodgetts, Richards, SC, Nutt, D.J., P Kellam, Peveler, R.C., Sinclair, L.I., the Collaborative Clinical Study, Group, Puri, B.K., Langford, PR, Harrison, T. J., Nutt, DJ, Weir, W., Montgomery, J, Richards, S. C. M., Kerr, J.R., Kerr, J. R., Petty, R, Richards, S.C.M., Morgan, R., Devanur, L. D., Chia, J. K., Hodgetts, A, Harrison, T.J, Harrison, TJ, Kerr, J.R, S T Holgate, Kellam, P, Holgate, ST, Axford, J. S., null null, Main, J., Collaborative Clinical Study Group, McDermott, C.R., The Collaborative Clinical Study Group, J Montgomery, Christian, P, Devanur, L.D, T J Harrison, Smith, A.P., Langford, P. R., Kellam, P., Kerr, JR, McDermott, C. R., Montgomery, J., Daymond, T., L I Sinclair, Enlander, D., P Christian, Burke, B, Sinclair, LI, B Burke, Sinclair, L. I., Nutt, D. J., Burke, B., Ayres, J.G., L D Devanur, Holgate, S. T., D J Nutt, Chia, J.K., Christian, P., C R McDermott, Ayres, J. G., Puri, B. K., Thomas, M., Nutt, D.J, Petty, R., McDermott, CR, Sinclair, L.I, J R Kerr, Devanur, LD, McDermott, C.R, Harrison, T.J., S C M Richards, P R Langford, Honeybourne, D., Richards, SCM, Thomas, M, D Devanur, L, Richards, S.C.M, Clinical Study Grp   +90 more
core   +1 more source

Chronic fatigue syndrome – challenge in diagnosis and management: a literature review

Journal of Medical Science, 2023
Introduction. Chronic fatigue syndrome is a disease that includes a number of various symptoms, among which the most characteristic symptom is fatigue.
Adrianna Nieciecka, Julia Tomys-Składowska, Magdalena Lamch, Monika Jabłońska, Natalia Błasik, Marta Janiszewska, Agata Wójcik-Kula   +6 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Absence of xenotropic murine leukaemia virus-related virus in UK patients with chronic fatigue syndrome [PDF]

, 2010
Background: Detection of a retrovirus, xenotropic murine leukaemia virus-related virus (XMRV), has recently been reported in 67% of patients with chronic fatigue syndrome. We have studied a total of 170 samples from chronic fatigue syndrome patients from
Kerr Jonathan R, Breuer, J, Groom, HC, Randal Edward, Makinson, Kerry, Frank M Mattes, Baptista, Sarah, Kerr, JR, Groom, Harriet C.T., Bishop Kate N, Boucherit, VC, Kate N Bishop, Gow, John W., Gow, JW, Stoye Jonathan P, Judith Breuer, Baptista, S, Virginie C Boucherit, Kerry Makinson, Randal, Edward, Groom Harriet CT, Gow John W, Makinson Kerry, Hagan Suzanne, Groom, HCT, Makinson, K, Bishop, KN, Baptista Sarah, Suzanne Hagan, Harriet CT Groom, John W Gow, Boucherit, Virginie C., Edward Randal, Breuer Judith, Boucherit Virginie C, Randal, E, Hagan, S, Jonathan R Kerr, Mattes, Frank M., Hagan, Suzanne; id_orcid, Stoye, JP, Mattes Frank M, Sarah Baptista, Jonathan P Stoye, Mattes, FM   +44 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross‐Sectional Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato, Alessia Giugno, Miriam Sturniolo, Enrico Fratto, Pio Zoleo, Francesca Felicia Operto, Ilaria Sammarra, Antonio Gambardella   +7 more
wiley   +1 more source