Results 31 to 40 of about 478,294 (214)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Ground-state properties of weakly bound helium-alkali trimers [PDF]
, 2017 Weakly bound triatomic molecules consisting of two helium atoms and one alkali metal atom are studied by means of the diffusion Monte Carlo method. We determined the stability of 4He2A, 4He3HeA, and 3He2A, where A is one of the alkali atoms Li, Na, K, Rb,
Boronat Medico, Jordi +3 more
core +2 more sources
A Violência no Local de Trabalho em Instituições de Saúde: Um Estudo Monocêntrico sobre Causas, Consequências e Estratégias de Prevenção [PDF]
, 2020 Introduction: Workplace violence is one of the main risk factors in the professional world. Healthcare workers are at higher risk when compared to other sectors.
Antão, HS +6 more
core +3 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Hematology, Transfusion and Cell TherapyIntrodução: As Coagulopatias Hereditárias Raras (CHR) correspondem a aproximadamente 5% de todas as coagulopatias hereditárias e incluem deficiências de fatores de coagulação diferentes dos fatores VIII, IX e do fator de von Willebrand, que são ...
CW Erthal +9 more
doaj +1 more source
Velhos e novos anticoagulantes orais. Perspetiva farmacológica
Revista Portuguesa de Cardiologia, 2012 Resumo: A terapêutica anticoagulante oral está em mudança. A varfarina e o acenocumarol constituem ainda o padrão anticoagulante oral em muitos contextos clínicos.
Pedro Marques da Silva
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Old and New Oral Anticoagulants. Pharmacological Perspective [PDF]
, 2012 A terapêutica anticoagulante oral está em mudança. A varfarina e o acenocumarol constituem ainda o padrão anticoagulante oral em muitos contextos clínicos. Mas, face às limitações dos antivitamínicos K, resultantes do lento início de ação farmacológica,
Marques da Silva, P
core +1 more source
Validação da versão portuguesa da Escala de Motivação Situacional (SIMS) em contextos académicos [PDF]
, 2017 The Situational Motivation Scale (SIMS), seeks to evaluate the motivation experienced when carrying out a specific task. The purpose of this research was to validate a Portuguese-language version of the scale, using a sample of 409 students, by ...
Gamboa, Vitor +2 more
core +3 more sources