Results 91 to 100 of about 1,368 (248)

Tempo Próprio Efetivo em Circuitos Elétricos e Eletrônicos: Critério Energia--Causal, Operador \(K\), Fator \(G(K)\) e Protocolos de Projeto

open access: yes
Este trabalho apresenta a versão operacional, em engenharia elétrica e eletrônica, do formalismo de tempo próprio efetivo derivado na Parte I. A tese central é que o tempo próprio de uma excitação circuital não deve ser identificado com atrasode grupo, fase, dispersão, tempo de propagação ou armazenamento isolado de energia.
openaire   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Erosividade da chuva e erodibilidade de Cambissolo e Latossolo na região de Lavras, sul de Minas Gerais Rainfall erosivity and erodibility of Cambisol (Inceptisol) and Latosol (Oxisol) in the region of Lavras, Southern Minas Gerais State, Brazil

open access: yesRevista Brasileira de Ciência do Solo, 2009
No Brasil, ainda são relativamente poucos os estudos envolvendo erodibilidade do solo, principalmente Cambissolos, dada a morosidade na obtenção dos resultados de experimentos com chuva natural.
Antonio Marcos da Silva   +4 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Efeito da estratégia de vida sobre as variações no conteúdo de energia de duas espécies de peixes (Brycon hilarii e Hypophthalmus edentatus), durante o ciclo reprodutivo = Effect of life strategy on the variations of energy content of two fish species (Brycon hilarii e Hypophthalmus edentatus) during their reproductive cycle

open access: yesActa Scientiarum: Biological Sciences, 2007
Com o objetivo de investigar diferenças no conteúdo de energia durante o ciclo reprodutivo, foram selecionados 54 exemplares de Brycon hilarii (k-estrategista) e 82 de Hypophthalmus edentatus (r-estrategista) em amostragens realizadas mensalmente ...
Vanessa Monteiro   +2 more
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Eficiência de misturas ternárias : aplicação do conceito do fator-k

open access: yes, 2012
A indústria de produção de cimento é atualmente uma das indústrias mais poluentes, contribuindo negativamente e de forma considerável na emissão de gases tóxicos para atmosfera. Existe, portanto, uma necessidade geral de redução da dependência e utilização do cimento a fim de minorar os seus efeitos no ambiente. Uma forma de diminuir a sua necessidade,
openaire   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

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