Results 31 to 40 of about 1,369 (247)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Avaliação de métodos indiretos de determinação da erodibilidade de Latossolos brasileiros
Existem três maneiras de se determinar a erodibilidade do solo (Fator K). A primeira envolve a determinação do fator K em condições de campo, sob chuva natural, a qual é onerosa e muito demorada. O segundo método é semelhante ao primeiro, porém baseia-se
SILVA MARX LEANDRO NAVES +3 more
doaj
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Objetiva-se avaliar o efeito da carga parasitária de Rondonia rondoni sobre o fator de condição de armados, Pterodoras granulosus. Foram necropsiados 51 espécimes de armados, coletados no rio Paraná (Porto Rico/Paraná). Para as análises, utilizaram-se os
Priscila Gôngora Dias +4 more
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
O objetivo deste trabalho foi mapear e analisar a susceptibilidade erosiva da bacia do rio Carinhanha por meio da aplicação da Equação Universal de Perda de Solo (EUPS), a fim de subsidiar o planejamento territorial ambiental na área.
Kelly Maria Resende Borges +4 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Este trabalho é parte do projeto de estudo detalhado do Complexo Granítico Cunhaporanga (CGC), neoproterozoico, aflorante na região do Arco de Ponta Grossa (estado do Paraná, SE do Brazil).
Horstpeter Herberto Gustavo José Ulbrich +5 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source

