Results 91 to 100 of about 377 (198)
Este trabalho apresenta a versão operacional, em engenharia elétrica e eletrônica, do formalismo de tempo próprio efetivo derivado na Parte I. A tese central é que o tempo próprio de uma excitação circuital não deve ser identificado com atrasode grupo, fase, dispersão, tempo de propagação ou armazenamento isolado de energia.
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
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Revista Brasileira de Ciência do Solo, 2009 No Brasil, ainda são relativamente poucos os estudos envolvendo erodibilidade do solo, principalmente Cambissolos, dada a morosidade na obtenção dos resultados de experimentos com chuva natural.
Antonio Marcos da Silva +4 more
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
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Acta Scientiarum: Biological Sciences, 2007 Com o objetivo de investigar diferenças no conteúdo de energia durante o ciclo reprodutivo, foram selecionados 54 exemplares de Brycon hilarii (k-estrategista) e 82 de Hypophthalmus edentatus (r-estrategista) em amostragens realizadas mensalmente ...
Vanessa Monteiro +2 more
doaj
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
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Eficiência de misturas ternárias : aplicação do conceito do fator-k
, 2012 A indústria de produção de cimento é atualmente uma das indústrias mais poluentes, contribuindo negativamente e de forma considerável na emissão de gases tóxicos para atmosfera. Existe, portanto, uma necessidade geral de redução da dependência e utilização do cimento a fim de minorar os seus efeitos no ambiente. Uma forma de diminuir a sua necessidade,
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
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Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
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