Results 111 to 120 of about 2,461,573 (347)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Evaluating fault tolerance in security requirements of web services.

open access: yes, 2012
It is impossible to identify all of the internal and external security faults (vulnerabilities and threats) during the security analysis of web services.
Wan Ab. Rahman, Wan Nurhayati   +6 more
core   +1 more source

Activity Based Tolerance Allocation (ABTA) – Driving tolerance synthesis by evaluating its global cost [PDF]

open access: yes, 2009
This paper deals with tolerance allocation driven by an activity based approach. Its main objective is to rationally give a good indicator of the relevance of tolerances values fixed by designers.
MARTIN, Patrick   +3 more
core   +1 more source

The optimization of global fault tolerant trajectory for redundant manipulator based on self-motion

open access: yesMATEC Web of Conferences, 2015
The redundancy feature of manipulators provides the possibility for the fault tolerant trajectory planning. Aiming at the completion of the specific task, an algorithm of global fault tolerant trajectory optimization for redundant manipulator based on ...
Zhang Jian   +4 more
doaj   +1 more source

Software fault tolerance

open access: yesInformatica, 1990
Summary: A fault-tolerant software unit is composed of \(N\geq 2\) diverse member units, usually developed by \(N\) separate teams, and an execution environment. The development process employs diversity requirements, communication protocols, and inter-team isolation rules to promote the greatest possible independence of team efforts and diversity ...
openaire   +2 more sources

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Fault tolerance of Mobius cubes under two forbidden fault set models

open access: yes, 2004
An n-dimensional Mobius cube, 0MQ(n) or 1MQ(n), is a variation of n-dimensional cube Q(n) which possesses many attractive properties such as significantly smaller communication delay and stronger graph-embedding capabilities. In some practical situations,
Megson, G. M.   +3 more
core   +1 more source

Scalable fault tolerance [PDF]

open access: yes, 1996
As communication networks grow, existing fault handling tools become increasingly unaffordable. In many cases the reason is that they involve global measures such as global time-outs or reset procedures, and their cost grows with the size of the network. Rather, for a fault handling mechanism to scale to large networks, it should involve local measures,
openaire   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

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