Results 191 to 200 of about 21,501 (222)

How quantum computing can enhance biomarker discovery. [PDF]

Patterns (N Y)
Flöther FF, Blankenberg D, Demidik M, Jansen K, Krishnakumar R, Krishnakumar R, Laanait N, Parida L, Saab CY, Utro F.   +9 more
europepmc   +1 more source

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

Advanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies, Emanuele Nicotra, Kefan Zhu, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Phuoc Thien Phan, Jingjing Wan, Patrick Pruscino, Hermione Truong, Jelena Rnjak‐Kovacina, Hoang‐Phuong Phan, Christopher Hayward, Nigel Hamilton Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Encoding a magic state with beyond break-even fidelity. [PDF]

Nature
Gupta RS, Sundaresan N, Alexander T, Wood CJ, Merkel ST, Healy MB, Hillenbrand M, Jochym-O'Connor T, Wootton JR, Yoder TJ, Cross AW, Takita M, Brown BJ.   +12 more
europepmc   +1 more source

Multicohort Validation of Gut Microbiome Signatures for Cholangiocarcinoma Diagnosis and Functional Characterization of Bifidobacterium Pseudocatenulatum

Advanced Science, EarlyView.
This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao, Jianwen Jiang, Ruiqing Zhang, Dongya Zhang, Chenchen Zhang, Ang Li, Haifeng Lu, Hua Zhang, Lin Zhou, Wenzhi Guo, Peihao Wen, Jianfeng Xue, Jie Pan, Tuerganaili Aji, Zhou Lan, Xianzhi Jiang, Shusen Zheng, Zujiang Yu, Zhigang Ren   +18 more
wiley   +1 more source

Self-rerouting sensor network for electronic skin resilient to severe damage. [PDF]

Nat Commun
Ozaki T, Ohta N, Fujiyoshi M.
europepmc   +1 more source

Double resolvability parameters of fosmidomycin anti-malaria drug and exchange property. [PDF]

Heliyon
Ismail R, Ali S, Azeem M, Zahid MA.
europepmc   +1 more source

Intelligent ship traffic supervision system based on distributed blockchain and federated reinforcement learning for collaborative decision optimization. [PDF]

Sci Rep
Wei Z, Rongjun P, Shijie W, Meiqing C.
europepmc   +1 more source

Robust federated learning for cloud environments using evolutionary optimization and blockchain. [PDF]

Sci Rep
Panimalar SP, Gunasundari S.
europepmc   +1 more source

Improving network resilience against DDoS attacks: A fuzzy TOPSIS-based quantitative assessment approach. [PDF]

Heliyon
Almotiri SH.
europepmc   +1 more source