Results 201 to 210 of about 539,809 (286)

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

Long-period microseismicity reveals cryptic earthquake-triggered fluid activity can facilitate caldera eruptions. [PDF]

Nat Commun
Song Z, Bell AF, LaFemina PC, Butcher S, Ruiz M, Hernández S, Gregg PM, Tan YJ.   +7 more
europepmc   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Little to no active faulting likely at Europa's seafloor today. [PDF]

Nat Commun
Byrne PK, Dawson HG, Klimczak C, Regensburger PV, Crane KT, Catalano JG, Elder CM, Foley BJ, German CR, Green AP, Hemingway DJ, Melwani Daswani M, Panning MP, Randolph-Flagg N, Sherwood Lollar B, Skemer P, Vance SD, Wiens DA.   +17 more
europepmc   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Tephra seismites-Understanding seismic hazard of hidden faults by analyzing liquefied tephra layers in lakes. [PDF]

Sci Adv
Kluger MO, Melchert RA, Moratalla JM, Ilanko T, Lowe DJ, Moon VG, Villamor P, Chaneva J, Ross N, Orense RP.   +9 more
europepmc   +1 more source

Enhancing the resolution of microseismicity through dense array monitoring in complex extensional settings. [PDF]

Sci Rep
Scotto di Uccio F, Muzellec T, Scala A, De Landro G, Camanni G, Carotenuto F, Elia L, Picozzi M, Zollo A, Strumia C, Beroza GC, Festa G.   +11 more
europepmc   +1 more source

Demonstration of measurement-free universal logical quantum computation. [PDF]

Nat Commun
Butt F, Pogorelov I, Freund R, Steiner A, Meyer M, Monz T, Müller M.   +6 more
europepmc   +1 more source

A numerical appraisal of the 'fault-valve' model of origin of lode-type gold deposits. [PDF]

Sci Rep
Bhuyan S, Panigrahi MK.
europepmc   +1 more source

Multidisciplinary approaches to lithological discrimination and structural mapping for mineral resource assessment. [PDF]

Sci Rep
Elfadly MA, Abdelrady M, Decarlis A, Khudeir AA, El-Rus MAA, Abbas H, Hadek HHE, Ibraheem IM, Shebl A.   +8 more
europepmc   +1 more source