Results 61 to 70 of about 22,345,845 (193)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Robust Generalized Transient-Extracting Transform for Time–Frequency Feature Extraction

Fractal and Fractional
Time–frequency analysis (TFA) facilitates the extraction of instantaneous frequency (IF) features from non-stationary signals. Transient Extraction Transform (TET) produces highly concentrated time–frequency representations (TFRs) for pulse-like fault ...
Junbo Long, Dongyun Luo, Daifeng Zha, Honglian Wu, Tong Shu, Hongshe Fan   +5 more
doaj   +1 more source

High-reliability fault tolerant digital systems in nanometric technologies: Characterization and design methodologies [PDF]

, 2012
This paper reports the main contribution of a project devoted to the definition of techniques to design and evaluate fault tolerant systems implemented using the SoPC paradigm, suitable for missionand safety-critical application environments.
Gerardin S., C. Metra, Rossi D, PACCAGNELLA, ALESSANDRO, Miele, A, Sterpone, Luca, Bagattin, M., S. Gerardin, Gerardin, S, Sandionigi C., Sterpone L., Sterpone L, Omana M., Salsano, A, ROSSI, DANIELE, Gerardin, S., Metra, C., GERARDIN, SIMONE, Bolchini, C, A. Miele, Ottavi M, Sonza Reorda, M., Bagatin M, Sandionigi, C, M. Bagatin, A. Paccagnella, MIELE, ANTONIO ROSARIO, Pontarelli, S., Miele A., C. Sandionigi, M. Violante, L. Sterpone, Gerardin S, Miele A, Paccagnella, A, Salsano A., Violante M, Ottavi M., Violante M., Bagatin, M., Sandionigi, C., Reorda M, SALSANO, ADELIO, Pontarelli S, OMANA, MARTIN EUGENIO, Bolchini, C., BAGATIN, MARTA, Bagatin M., C. Bolchini, Violante, M., Salsano A, Omana, M, Bagatin, M, Sonza Reorda M, Rossi D., Reorda, M, Paccagnella A., Omana, M., A. Salsano, PONTARELLI, SALVATORE, Violante, Massimo, S. Pontarelli, BOLCHINI, CRISTIANA, Metra C., Bolchini C, Omana M, Miele, A., Paccagnella, A., D. Rossi, Pontarelli S., Pontarelli, S, M. Ottavi, Reorda M. S., Reorda, M. Sonza, Sterpone, L., Sterpone, L, M. Sonza Reorda, Violante, M, Salsano, A., Sandionigi C, METRA, CECILIA, Metra, C, Ottavi, M., Rossi, D, OTTAVI, MARCO, M. Omana, Sonza Reorda, Matteo, Paccagnella A, Ottavi, M, Rossi, D., Bolchini C., Metra C   +91 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Fault analysis of leakage protection of smart low-voltage feed switch and its reformatio

Gong-kuang zidonghua, 2013
For faults in leakage protection of smart low-voltage feed switch of Nantun Coal Mine, the paper analyzed leakage protection principle and causes of the faults, and proposed reformation schemes: increase zero sequence current by additional capacitance at
GUAN Zhen-xiang, WANG Guang-sheng, JIANG Tao, LIU Shi-gang, ZHAI Dong, FAN Xin-liu   +5 more
doaj  

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Implications of fault current limitation for electrical distribution networks [PDF]

, 2010
This paper explores the potential future need for fault current limitation in the UK's power system, and some of the technical implications of this change.
Blair, S.M., Bright, C.G., Burt, G.M., Teo, A., Roscoe, A.J., Booth, C.D.   +5 more
core   +2 more sources

A New Transformer‐Less Buck‐Boost Converter With Reliability Assessment Using the Improved Markov Model

Engineering Reports
This work proposes a new continuous input current cubic gain buck‐boost converter with a simple structure and reduced components. The converter has minimal components consisting of a twin‐switch configuration with a broad range of duty‐cycle operations ...
Ifham H. Malick, Mohammad Zaid, Javed Ahmad, Chang‐Hua Lin, Marwan Ahmed Abdullah Alasali   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source