Results 61 to 70 of about 148,579 (316)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Implications of fault current limitation for electrical distribution networks

open access: yes, 2010
This paper explores the potential future need for fault current limitation in the UK's power system, and some of the technical implications of this change.
Blair, S.M.   +11 more
core   +1 more source

Evaluating the use of reference run models in fault injection analysis [PDF]

open access: yes, 2009
Fault injection (FI) has been shown to be an effective approach to assessing the dependability of software systems. To determine the impact of faults injected during FI, a given oracle is needed.
Jhumka, Arshad   +4 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Line-to-Line Fault Analysis and Location in a VSC-Based Low-Voltage DC Distribution Network

open access: yesEnergies, 2018
A DC cable short-circuit fault is the most severe fault type that occurs in DC distribution networks, having a negative impact on transmission equipment and the stability of system operation. When a short-circuit fault occurs in a DC distribution network
Shi-Min Xue, Chong Liu
doaj   +1 more source

Decentralized Plug-and-Play Protection Scheme for Low Voltage DC Grids

open access: yesEnergies, 2020
Since the voltages and currents in dc grids do not have a natural zero-crossing, the protection of these grids is more challenging than the protection of conventional ac grids. Literature presents several unit and non-unit protection schemes that rely on
Nils H. van der Blij   +5 more
doaj   +1 more source

Phase-shift Fault Analysis of Grain v1 [PDF]

open access: yesInternational Journal of Electronics and Telecommunications, 2018
This paper deals with the phase-shift fault analysis of stream cipher Grain v1. We assume that the attacker is able to desynchronize the linear and nonlinear registers of the cipher during the keystream generation phase by either forcing one of the ...
Viliam Hromada, Pethő Tibor
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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