Results 71 to 80 of about 6,022,636 (288)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Fault current limiter of VSC-HVDC systems using variable resistive bridge controller

, 2021
This paper proposes a fuzzy logic controller (FLC) based variable resistive bridge type fault current limiter (VR-BFCL) to minimize the impact of faults on voltage source converter high voltage direct current (VSC-HVDC) systems.
AL-Ismail, FS, Md. Shafiul Alam, Md Alamgir Hossain, Fahad Saleh AL-Ismail, Alam, MS, M.A. Abido, Hossain, MA, Abido, MA   +7 more
core   +1 more source

Superconducting Fault Current Limiters for HVDC Systems

Energy Procedia, 2015
AbstractHigh-voltage direct current (HVDC) transmission systems using Voltage-Source Converters (VSC) are widely recognized as offering significant potential for long distance high power delivery, particularly for offshore wind farm connections. One of the barriers for the development of multi-terminal HVDC systems is the lack of technologies which ...
Pei, Xiaoze, Smith, Alexander; id_orcid 0000-0001-6782-4627, Barnes, Michael   +2 more
openaire   +3 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Fault Current Limitation Coordination in Electric Power Grid With Superconducting Fault Current Limiters

IEEE Transactions on Applied Superconductivity, 2018
This paper proposes the concept of “fault current limitation coordination” in a future electric power grid with multiple superconducting fault current limiters (SFCL). Not only the fault current limitation of each SFCL on a transmission line, but also the transient stability of the grid with SFCLs should be taken into account, because the disturbance ...
Naoki Hayakawa, Yuya Maeno, Hiroki Kojima   +2 more
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Fault Current Limiter Controller for the Protection of Inverter Based Distributed Generation

, 2020
Power systems are becoming more vulnerable to different faults due to high current. This threat is increasing day by day due to the shift of power system from conventional generation to power electronic-based distributed generation.
Islam, MA, Rahman, A, Alam, MS, Al-Ismail, FS, Hossain, MA   +4 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Limitation of Fault Currents by Positioning of Superconducting Fault Current Limiter in AC and DC Microgrid

International Journal of Advanced Research in Electrical, Electronics and Instrumentation Engineering, 2015
Different types of distributed generation (DG) sources could be connected to the main power grid in order to improve the reliability of the power system, in a smart grid. The association of ac and dc distribution grid are assigned for the efficient connection of renewable power resources.
K. Sreedhar Kumar, J N Chandra Sekhar
openaire   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source