Results 81 to 90 of about 12,003 (292)

Impact of increased distributed generation on fault levels and the network equipment [PDF]

open access: yes, 2014
Attention towards the development of Distributed Generation (DG) is globally high. UK's concentration is to use sustainable and renewable sources to generate electricity thereby protecting the environment from getting polluted. In this paper, Distributed
Bhavanam, YR, Shahrazad, M
core  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Behavior Of Superconducting Fault Current Limiter Under Fault Condition

open access: yes, 2017
Now a days due to increase in electricity demand for the purpose of industrialization, agriculture, domestic and educational etc there exists more chances of fault occurance. The Faults occurs due to insulation damaging, breaking of conductor, short circuit, lightning etc.
KARUNA L. BARI, S. M. SHEMBEKAR
openaire   +1 more source

Resistive DC fault current limiter

open access: yesThe Journal of Engineering, 2017
The DC fault current of bipolar short‐circuit fault rises rapidly due to the low damping performance of the modular multilevel converter‐high‐voltage DC (MMC‐HVDC) system. It is of great engineering significance to study the DC fault current limiter (FCL) in HVDC systems for suppressing the DC fault current, resulting in making the DC circuit breaker ...
Xie Sujuan, Qiu Yufeng, Bi Tianshu
openaire   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Використання явища високотемпературної надпровідності у струмообмежуючому реакторі [PDF]

open access: yes, 2012
У статті проаналізована конструкція струмообмежуючого реактора з надпровідними екраном і обмоткою. Теоретично розглянуто роботу такого надпровідного обмежувача струму короткого замикання в основних режимах.
Гончаров, Євген Вікторович   +1 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy