Results 81 to 90 of about 12,041 (292)

Impact of increased distributed generation on fault levels and the network equipment [PDF]

open access: yes, 2014
Attention towards the development of Distributed Generation (DG) is globally high. UK's concentration is to use sustainable and renewable sources to generate electricity thereby protecting the environment from getting polluted. In this paper, Distributed
Bhavanam, YR, Shahrazad, M
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Behavior Of Superconducting Fault Current Limiter Under Fault Condition

open access: yes, 2017
Now a days due to increase in electricity demand for the purpose of industrialization, agriculture, domestic and educational etc there exists more chances of fault occurance. The Faults occurs due to insulation damaging, breaking of conductor, short circuit, lightning etc.
KARUNA L. BARI, S. M. SHEMBEKAR
openaire   +1 more source

Resistive DC fault current limiter

open access: yesThe Journal of Engineering, 2017
The DC fault current of bipolar short‐circuit fault rises rapidly due to the low damping performance of the modular multilevel converter‐high‐voltage DC (MMC‐HVDC) system. It is of great engineering significance to study the DC fault current limiter (FCL) in HVDC systems for suppressing the DC fault current, resulting in making the DC circuit breaker ...
Xie Sujuan, Qiu Yufeng, Bi Tianshu
openaire   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Використання явища високотемпературної надпровідності у струмообмежуючому реакторі [PDF]

open access: yes, 2012
У статті проаналізована конструкція струмообмежуючого реактора з надпровідними екраном і обмоткою. Теоретично розглянуто роботу такого надпровідного обмежувача струму короткого замикання в основних режимах.
Гончаров, Євген Вікторович   +1 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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