Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
Fault Detection and Diagnosis in Industrial Processes with Variational Autoencoder: A Comprehensive Study. [PDF]
Sensors (Basel), 2021 Zhu J, Jiang M, Liu Z.
europepmc +1 more source
Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source
Deep Convolutional Neural Network with Deconvolution and a Deep Autoencoder for Fault Detection and Diagnosis. [PDF]
ACS Omega, 2022 Kanno Y, Kaneko H.
europepmc +1 more source
Real-time diagnostics for a reusable rocket engine [PDF]
A hierarchical, decentralized diagnostic system is proposed for the Real-Time Diagnostic System component of the Intelligent Control System (ICS) for reusable rocket engines.
Duyar, A., Guo, T. H., Merrill, W.
core +1 more source
Gearbox fault diagnosis under different operating conditions based on time synchronous average and ensemble empirical mode decomposition [PDF]
, 2009 In this paper, a new method is proposed by combining ensemble empirical mode decomposition (EEMD) with order tracking techniques to analyse the vibration signals from a two stage helical gearbox.
Ball, A +4 more
core
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Hybrid Random Forest and Support Vector Machine Modeling for HVAC Fault Detection and Diagnosis. [PDF]
Sensors (Basel), 2021 Tun W, Wong JK, Ling SH.
europepmc +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Real-Time Fault Detection and Diagnosis of CaCO3 Reactive Crystallization Process by Electrical Resistance Tomography Measurements. [PDF]
Sensors (Basel), 2021 Aghajanian S +5 more
europepmc +1 more source