Results 41 to 50 of about 13,671 (263)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Applications of Artificial Intelligence in Computer Vision for the Identification of Fabric Faults in Textile Production

Sir Syed University Research Journal of Engineering and Technology
Fabric production faces major deficiencies in the identification of faults in traditional systems owing to human errors and a lack of verification. The conventional system identifies faults using manual examination techniques, which consume labor time ...
Khurram Iqbal, Umm E Laila, Syed Atir Iftikhar, Mohsin Malik, Shayan Arif   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Intelligent Ensemble Learning-Based Fault Diagnosis, Location, and Protection of Series-Compensated Transmission Lines for Smart Power Grid Applications

Energies
Accurate fault diagnosis and protection of series-compensated transmission lines remain challenging due to the nonlinear behavior of series capacitors and associated protective devices, which degrade the performance of conventional protection relays ...
Janardhan Rao Moparthi, Krishna Naick Bhukya, Raghavendra Naik Kethavath, Mohan Lal Kolhe, Jereb Borut   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Fault Identification of Chemical Processes Based on k-NN Variable Contribution and CNN Data Reconstruction Methods

Sensors, 2019
Data-driven fault detection and identification methods are important in large-scale chemical processes. However, some traditional methods often fail to show superior performance owing to the self-limitations and the characteristics of process data, such ...
Guo-Zhu Wang, Jing Li, Yong-Tao Hu, Yuan Li, Zhi-Yong Du   +4 more
doaj   +1 more source

Weak Fault Diagnosis Method of Rolling Bearings Based on Variational Mode Decomposition and a Double-Coupled Duffing Oscillator

Applied Sciences, 2023
Aiming at the problems of the low detection accuracy and difficult identification of the early weak fault signals of rolling bearings, this paper proposes a method for detecting the early weak fault signals of rolling bearings based on a double-coupled ...
Shijie Shan, Jianming Zheng, Kai Wang, Ting Chen, Yuhua Shi   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Non-Fault Detection Scheme Before Reclosing Using Parameter Identification for an Active Distribution Network

Energies
The distribution network line has the risk of an unsuccessful three-phase blind reclosing in permanent fault. Based on the response of the inverter of the distributed generation (DG) to the short-term low-frequency voltage disturbance to the line to be ...
Zhebin Sun, Sileng A, Xia Sun, Shuang Zhang, Dinghua Liu, Wenquan Shao   +5 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source