Results 121 to 130 of about 252,496 (356)

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Reaction Wheels Fault Isolation Onboard 3-Axis Controlled Satel-lite using Enhanced Random Forest with Multidomain Features

, 2021
Afshin Rahimi, Mofiyinoluwa O. Folami
openalex   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Advanced fault detection methodologies and communication protocols for DC micro grid -A technical review

Results in Engineering
DC microgrids are increasingly adaptable to contemporary electrical systems due to their superior capacity to integrate distributed energy resources (DER) and enhance the overall stability of the grid.
Athira Earath Shivadasan, Prabhakar Karthikeyan Shanmugam   +1 more
doaj   +1 more source

Intelligent fault isolation and diagnosis for communication satellite systems [PDF]

Discussed here is a prototype diagnosis expert system to provide the Advanced Communication Technology Satellite (ACTS) System with autonomous diagnosis capability.
Durkin, John, Petrik, Edward J., Tallo, Donald P.   +2 more
core   +1 more source

Practical Model-Based Diagnosis with Qualitative Possibilistic Uncertainty [PDF]

, 2013
An approach to fault isolation that exploits vastly incomplete models is presented. It relies on separate descriptions of each component behavior, together with the links between them, which enables focusing of the reasoning to the relevant part of the ...
Cayrac, Didier, Dubois, Didier, Prade, Henri   +2 more
core  

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Automatic Detection of Electric Power Troubles (ADEPT) [PDF]

ADEPT is an expert system that integrates knowledge from three different suppliers to offer an advanced fault-detection system, and is designed for two modes of operation: real-time fault isolation and simulated modeling.
Anderson, Audie, Brady, Mike, Ford, Donnie, Patrick, Clint, Wang, Caroline, Zeanah, Hugh   +5 more
core   +4 more sources