Results 121 to 130 of about 1,108,433 (294)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

A general formulation for fault detection in stochastic continuous-time dynamical systems [PDF]

open access: yes, 2008
In this work, a general formulation for fault detection in stochastic continuoustime dynamical systems is presented. This formulation is based on the definition of a pre-Hilbert space so that orthogonal projection techniques, based on the statistics of ...
Zufiria Zatarain, Pedro José
core  

Fault-Tolerant Model Predictive Control with Active Fault Isolation

open access: yes, 2013
A robust control method is presented for linear systems subject to input and state constraints, bounded disturbances and measurement noise, and discrete faults in sensors, actuators, and system dynamics.
J. K. Scott   +7 more
core   +1 more source

Filter for detecting and isolating faults for a nonlinear system [PDF]

open access: yes, 2003
In the paper the problem of detecting and isolating multiple faults for nonlinear systems is considered. A strategy of state filtering is derived in order to detect and isolate multiple faults which appear simultaneously or sequentially in a discrete ...
Dutka, A., Giovanini, L.
core   +1 more source

Software Fault Isolation for Robust Compilation

open access: yesCoRR, 2018
Memory corruption vulnerabilities are endemic to unsafe languages, such as C, and they can even be found in safe languages that themselves are implemented in unsafe languages or linked with libraries implemented in unsafe languages. Robust compilation mitigates the threat of linking with memory-unsafe libraries. The source language is a C-like language,
openaire   +2 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

SENSOR/ACTUATOR FAULT DETECTION, ISOLATION AND ACCOMMODATION APPLIED TO UAV MODEL

open access: yesHavacılık ve Uzay Teknolojileri Dergisi, 2016
In this study sensor/actuator fault detection, isolation and accommodation is performed using innovation sequence analysis in a small Unmanned Aerial Vehicle (UAV) model.
Sıtkı Yenal Vural, Cengiz Hacızade
doaj  

A novel wide-area fault isolation scheme for regional power systems with changeable network topologies

open access: yesInternational Journal of Electrical Power & Energy Systems
Existing Wide-Area Fault Isolation (WAFI) approaches, enabled by the Wide-Area Backup Protection (WABP) system, address the selectivity and coordination limitations of traditional local information-based fault isolation by offering a system-wide ...
Guangxiao Zhang, Xiaoyang Tong
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

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