Results 71 to 80 of about 846,547 (352)

Quantifying offshore fore-arc deformation and splay-fault slip using drowned Pleistocene shorelines, Arauco Bay, Chile [PDF]

open access: yes, 2017
Indexación: Web of Science; Scopus.Most of the deformation associated with the seismic cycle in subduction zones occurs offshore and has been therefore difficult to quantify with direct observations at millennial timescales.
Argandoña, B.   +6 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

An Automated Fault Tree Generation Approach With Fault Configuration Based on Model Checking

open access: yesIEEE Access, 2018
Fault tree generation technology is a key issue for safety analysis of large complex systems. Traditional safety analysis methods usually describe the origin, propagation, or concrete behavior of the fault and do not portray the constraints between ...
Lisong Wang   +4 more
doaj   +1 more source

Frictional Stabilities on Induced Earthquake Fault Planes at Fox Creek, Alberta: A Pore Fluid Pressure Dilemma

open access: yes, 2019
Earthquakes induced during hydraulic fracturing operations have occurred in a number of locales. However, in-situ studies aimed to discern the triggering mechanism remains exclusively statistical in their nature.
Schmitt, Douglas R.   +2 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

What does fault tolerant Deep Learning need from MPI?

open access: yes, 2017
Deep Learning (DL) algorithms have become the de facto Machine Learning (ML) algorithm for large scale data analysis. DL algorithms are computationally expensive - even distributed DL implementations which use MPI require days of training (model learning)
Amatya, Vinay   +3 more
core   +1 more source

Robust Fault Detection of Switched Linear Systems with State Delays [PDF]

open access: yes, 2009
This correspondence deals with the problem of robust fault detection for discrete-time switched systems with state delays under an arbitrary switching signal.
Shi, Peng, Wang, Dong, Wang, Wei
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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