Results 71 to 80 of about 447,699 (304)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Research on primary frequency regulation and VSC-HVDC frequency synchronization control coordination method for large-scale hydropower DC export regional grid

International Journal of Electrical Power & Energy Systems
In asynchronous grid connection mode, the rotational inertia of the partitioned synchronized grid decreases, leading to prominent frequency stability issues.
Hongchun Shu, Huaibin Gao, Zongxue Shao, Yongzan Cui, Wei Zhao   +4 more
doaj   +1 more source

Intelligent power system protection data management [PDF]

, 2013
The Power Flow is the most important issue to ensure an efficient yet affordable system. To maintain a low failure electrical breakdown or blackout analysis of faults leads to appropriate protection settings which can be computed in order to select
Hanzah, Nurulhuda Hanzah
core  

Improved transient simulation of salient-pole synchronous generators with internal and ground faults in the stator winding [PDF]

, 2005
An improved model for simulating the transient behavior of salient-pole synchronous generators with internal and ground faults in the stator winding is established using the multi-loop circuit method.
Bi, D.Q., Howe, D., Wang, W.J., Wang, X.H., Zhu, Z.Q.   +4 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Fault section location of collector lines based on phase comparison of zero-sequence current using the Kaiser window

International Journal of Electrical Power & Energy Systems
To address the limitations of existing single-phase grounding fault location methods for collector lines in wind farms, especially their insufficient adaptability to multi-branch topologies, this paper proposes a fault section location method based on ...
Yue Dai, Hongchun Shu, Cheng Guan, Yutao Tang, Yiming Han   +4 more
doaj   +1 more source

ROCOV scheme for Fault Detection and Location in HVDC sytems [PDF]

, 2019
A reliable DC fault protection system is essential for the development of HVDC grids. Therefore, this paper deals with the voltage derivative ROCOV scheme to locate and detect DC faults.
Abarrategi, O., Díaz, J., Larruskain, D.M., Perez-Basante, A., Rubio, A.   +4 more
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Analysis of multiple lightning overvoltage on 110 kV transmission lines

Results in Engineering
As pointed out by the CIGRE TB 549 report issued by the International Power Grid Committee, >80 % of cloud-to-ground lightning are multiple lightning strokes (MLS), posing a severe threat to overhead transmission lines.
Yutao Tang, Haoming Liu, Hongchun Shu, Yue Dai, Yiming Han   +4 more
doaj   +1 more source

Implications of fault current limitation for electrical distribution networks [PDF]

, 2010
This paper explores the potential future need for fault current limitation in the UK's power system, and some of the technical implications of this change.
Blair, S.M., Booth, C.D., Bright, C.G., Burt, G.M., Roscoe, A.J., Teo, A.   +5 more
core   +1 more source