Results 51 to 60 of about 320,218 (310)

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Development characteristics and formation mechanism of ultra-deep carbonate fault-dissolution body in Shunbei area, Tarim Basin

Shiyou shiyan dizhi, 2021
As a spatial geological body, a strike-slip fault zone has a physically and chemically controlled compart- mentalization effect, which can form a unique fracture-cavity system with associated pore spaces inside the fault zone.
Haitao LÜ, Jun HAN, Jibiao ZHANG, Yongli LIU, Yingtao LI   +4 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Middle Pleistocene to Holocene activity of the Gondola Fault Zone (Southern Adriatic Foreland): deformation of a regional shear zone and seismotectonic implications [PDF]

, 1970
Recent seismicity in and around the Gargano Promontory, an uplifted portion of the Southern Adriatic Foreland domain, indicates active E–W strike-slip faulting in a region that has also been struck by large historical earthquakes, particularly along the ...
Ridente, D., Fracassi, U., Di Bucci, D., Trincardi, F., Valensise, G.   +4 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Analysis of Location of Villages in Relation to Rupture Zone (Case Study: North Qazvin Fault) [PDF]

مسکن و محیط روستا, 2021
This paper studies the shear zone of North Qazvin fault and investigates the location of rural settlements in this area. In selected sections, the presence of transverse valleys along the fault made it possible to investigate the evidence of shear zones ...
Saeed Mohammad Sabouri, Hossein Haji Ali Beigi, Morteza Talebian, Morteza Fatahi   +3 more
doaj  

Fault damage zones

Journal of Structural Geology, 2004
Abstract Damage zones show very similar geometries across a wide range of scales and fault types, including strike-slip, normal and thrust faults. We use a geometric classification of damage zones into tip-, wall-, and linking-damage zones, based on their location around faults. These classes can be sub-divided in terms of fault and fracture patterns
Kim, Y-S., Peacock, D.D.P., Sanderson, D.J.   +2 more
openaire   +3 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

THE KONYA FAULT ZONE

Selçuk Üniversitesi Mühendislik, Bilim ve Teknoloji Dergisi, 2004
Konya fay zonu, Konya batısında kuzeydoğu-güneybatı uzanımlı, doğuya eğimli, eğim atımlınormal faylar ile temsil edilir. Fay zonu yaklaşık 65 km uzunluğa sahip olup, Hatunsaray doğusundanbaşlayarak kuzeydoğuya Doğudağ doğusuna doğru uzanır. Fay zonu 5 km genişliğinde bir takımsüreksiz, birbirlerine az çok paralel faylardan oluşmaktadır. Fay zonu içinde
Aksoy, Rahmi, Eren, Yaşar
openaire   +2 more sources

Seismology inside the Fault Zone: Applications to Fault-Zone Properties and Rupture Dynamics [PDF]

Scientific Drilling, 2007
No abstract available. <br><br> doi:<a href="http://dx.doi.org/10.2204/iodp.sd.s01.04.2007" target="_blank">10.2204/iodp.sd.s01.04.2007</a>
Ellsworth, William L., Malin, Peter E., Imanishi, Kazutoshi, Roecker, Steven W., Nadeau, Robert, Oye, Volder, Thurber, Clifford H., Waldhauser, Felix, Boness, Namoi L., Hickman, Stephen H., Zoback, Mark D.   +10 more
openaire   +4 more sources