Results 31 to 40 of about 26,220 (311)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Preliminary study on the Late Quaternary activity of important active fault zones along the Yunnan-Tibet railway

open access: yes地震科学进展
The Yunnan-Tibet railway is located in the southeastern edge of the Tibetan Plateau, where tectonic plates collide and the terrain rapidly changes. Along the line, active faults develops, earthquakes occur frequently, and the intensity of earthquakes is ...
Xianbing Zhang   +6 more
doaj   +1 more source

The walls boundary fault zone and the MØre TrØndelag fault complex:: a case study of two reactivated fault zones. [PDF]

open access: yes, 2001
It is commonly observed that ancient faults or shear zones can become reactivated again and again, either within the same or even superimposed tectonic episodes, yet millions of years apart.
Watts, Lee Mark
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Integration of the GPR and radio-impedance techniques in studies of the Baikal rift zone

open access: yesГеодинамика и тектонофизика, 2019
Radiowave propagation techniqueshave been very rarely applied to investigate tectonic fault zones and geoelectric profilesof the Baikal rift zone. In our study, we used a combination ofground-penetrating radar (GPR) and radioimpedance techniquesin order ...
Yu. B. Bashkuev   +2 more
doaj   +1 more source

Geometry, evolution and scaling of fault relay zones in 3D using detailed observations from outcrops and 3D seismic data [PDF]

open access: yes, 2011
A new surface attribute was developed during the course of the thesis, which enables fault-related deformation – specifically, the apparent dip of mapped horizons measured in a direction perpendicular to the average strike of a fault array (here termed ...
Long, Jonathan James   +1 more
core  

Structural heterogeneity and permeability in faulted eolian sandstone: Implications for subsurface modeling of faults [PDF]

open access: yes, 2002
We determined the structure and permeability variations of a 4 km-long normal fault by integrating surface mapping with data from five boreholes drilled through the fault (borehole to tens of meters scale).
Shipton, Zoe K.   +9 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Active faulting in the Betic External Zones (SE, Spain): The Alcoy Fault Zone

open access: yesGeologica Acta
Evidence of active faulting is presented for a structure located in the eastern Betic External Zones (SE Spain). New fault data are provided for the Alcoy Fault Zone, whose Quaternary activity remains under debate. This study includes a detailed structural and geomorphic characterization, together with a preliminary palaeoseismological analysis.
Santamaría Pérez, Eva   +3 more
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy