Results 101 to 110 of about 279,410 (290)

VI. Fauna silvestre del Escudo Guayanés (Colombia- Venezuela)

open access: yes, 2018
El libro recoge los resultados de las investigaciones realizadas acerca de la fauna silvestre del Escudo Guayanés en ambos países. En el caso venezolano, desde hace varias décadas -podríamos hablar casi desde la mitad del siglo pasado- y en Colombia, de ...
Lentino, Miguel   +19 more
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

MEMORIAS 1ER Seminario Internacional de Investigadores en Fauna Silvestre

open access: yesRevista de la Facultad de Ciencias Agropecuarias, 2020
El programa de Medicina Veterinaria y Zootecnia de la Universidad de la Amazonia cuenta con un sello de fauna silvestre en su proceso de formación profesional, el cual se ve reflejado en los intereses de investigación y en la necesidad de interactuar con
Memorias Primer Seminario Fauna Silvestre
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Inventario Nacional Forestal y de Fauna Silvestre, Informe de resultados Panel 1

open access: yes, 2020
Este documento presenta el análisis de la información del Inventario Nacional Forestal y de Fauna Silvestre correspondiente al Panel 1 (20% de la muestra nacional) para los componentes: estado del bosque, biomasa, carbono y fauna silvestre de las ...
Servicio Nacional Forestal y de Fauna Silvestre
core   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

UAV-assisted counts of group size facilitate accurate population surveys of the Critically Endangered cao vit gibbon Nomascus nasutus

open access: yesOryx
Gibbons are often difficult to observe in dense forest habitats using traditional ground-based methods. This makes it challenging to estimate group sizes and, in turn, population sizes. This has proven to be a key constraint on accurate monitoring of the
Oliver R. Wearn   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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