Results 161 to 170 of about 251,145 (305)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

¿Que es SERFOR?

, 2014
Ficha Informativa distribuida por redes socialesFicha Informativa: Somos SERFOR o Servicio Nacional Forestal y de Fauna Silvestre, un organismo técnico especializado, comprometido con el manejo sostenible del Patrimonio Forestal y de Fauna Silvestre ...
Servicio Nacional Forestal y de Fauna Silvestre
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The Dam Removal Europe movement reaches Romania

Oryx
Paul Hac, Mihaela Faur-Poenar, Mircea Marginean   +2 more
doaj   +1 more source

Benthic fauna on the edge between different seas-signs of climate change in the Sound (Öresund)? [PDF]

PeerJ
Göransson P.
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Beyond Species Diversity: Functional Approaches Reveal Consistent Fauna Community Responses to Exotic Grass Invasion in Arid Lands. [PDF]

Ecol Evol
Ryan-Colton E, Wardle GM, Read JL, French K, Schlesinger CA.   +4 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Spatial and seasonal dynamics of aquatic macroinvertebrates and fish communities in relation to water quality variation in the Nile Valley, Egypt. [PDF]

Sci Rep
Baz MM, Riad SA, Gad ME, El-Barbary Y, Metawe DM, Hussein IE, Hikal WM, El-Sayed YA, Hassan FA, Selim A, Gattan HS, Alruhaili MH, Darwish AB.   +12 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Encontraste una Golondrina de mar?

, 2019
Venimos recibiendo muchos reportes de hallazgo de estas pequeñas aves. Ayudémoslas a regresar a su hogar .Revisa la ubicación de nuestras Administraciones Técnicas Forestal y de Fauna Silvestre: https://www.serfor.gob.pe/administraciones-tecnica ...
Servicio Nacional Forestal y de Fauna Silvestre
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