Results 231 to 240 of about 135,175 (300)

Trophic Relationships of Aquatic Species Offer Valuable Insights Into Shallow Lake Ecosystem Recovery. [PDF]

Ecol Evol
Qiao Y, Pang M, Lv M, Zhu T, Han W, Li Z, Lin X, Su P, Qu P, Zhang C.   +9 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Comparison of Hard Tick (Acari: Ixodidae) Fauna in Natural and Anthropogenic Habitats in Croatia. [PDF]

Insects
Krčmar S, Vucelja M, Pezzi M, Boljfetić M, Margaletić J, Bjedov L.   +5 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

An analytical synopsis of caddisfly (Insecta, Trichoptera) taxonomic history and progress in Canada and the United States. [PDF]

Zookeys
Hogan PN, Houghton DC, Murray-Stoker K, DeWalt RE, Rasmussen AK, Morse JC.   +5 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Origin and Genetic Diversity of <i>Barbatula</i> (Cypriniformes: Nemacheilidae) in Italy. [PDF]

Ecol Evol
Zanovello L, Eisendle D, Casari S, Ennemoser M, Grund H, Favrin G, Rossi S, Modesti A, Luchelli M, Rüber L, Meraner A, Gandolfi A.   +11 more
europepmc   +1 more source

Fauna parasitária de Geophagus brasiliensis (Perciformes: Cichlidae) em reservatórios do estado do Paraná, Brasil

, 2012
Sybelle Bellay, Bruno Hideo Saiki Silva, Ricardo Massato Takemoto, Maria de los Angeles Perez Lizama, Gilberto Cezar Pavanelli   +4 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Responses of grassland soil mesofauna to induced climate change. [PDF]

Sci Rep
Gruss I, Czarniecka-Wiera M, Świerszcz S, Szymura M, Szymura T, Raduła MW.   +5 more
europepmc   +1 more source