Results 11 to 20 of about 13,127 (167)

Favipiravir‐induced bradycardia: A case report

Clinical Case Reports
Key Clinical Message The purpose of this case report is to reveal one of the cardiovascular side effects of favipiravir, sinus bradycardia. Abstract Favipiravir has emerged as a potential treatment for COVID‐19, with its antiviral properties showing ...
Alireza Kashefizadeh, Laya Ohadi, Farbod Amiri, Maryam Abdolmaleki, Vahid Eslami, Mehrdad Jafari Fesharaki   +5 more
doaj   +2 more sources

Favipiravir Inhibits Mayaro Virus Infection in Mice

Viruses, 2021
Mayaro virus (MAYV) is an emergent alphavirus that causes MAYV fever. It is often associated with debilitating symptoms, particularly arthralgia and myalgia.
Michèle Bengue, Ai-rada Pintong, Florian Liegeois, Antoine Nougairède, Rodolphe Hamel, Julien Pompon, Xavier de Lamballerie, Pierre Roques, Valérie Choumet, Dorothée Missé   +9 more
doaj   +2 more sources

Use of Favipiravir in Covid-19 Patients: A Narrative Review [PDF]

JPSCR: Journal of Pharmaceutical Science and Clinical Research
COVID-19 is an acute respiratory disease resulting from the infection of SARS-COV-2 viruses and causes high morbidity, which requires appropriate treatment targets. Favipiravir is an antiviral that selectively inhibits RNA-dependent RNA polymerase (RdRp)
Vitarani Dwi Ananda Ningrum, Annisa Fitria, Fadiyah Ulfa Hanur   +2 more
doaj   +2 more sources

Follow-up of Favipiravir-Induced Nail Fluorescence: Implications for Nail and Drugs

Dermatology Practical & Conceptual, 2023
Introduction: Favipiravir creates fluorescence on nails, which can be seen with Wood's light. Objectives: The objectives of this study are to examine the properties of fluorescence in the nail due to favipiravir and to observe whether other drugs also
Hüsna Güder, Zeynep Güneş Özünal
doaj   +2 more sources

Favipiravir Treatment Prolongs Survival in a Lethal BALB/c Mouse Model of Ebinur Lake Virus Infection

Viruses
Orthobunyavirus is the largest and most diverse genus in the family Peribunyaviridae. Orthobunyaviruses are widely distributed globally and pose threats to human and animal health.
Jingke Geng, Nanjie Ren, Cihan Yang, Fei Wang, Doudou Huang, Sergio Rodriguez, Zhiming Yuan, Han Xia   +7 more
doaj   +2 more sources

Pharmacokinetic Assessment of Atazanavir and Favipiravir Following Echinacea Supplementation: A Controlled Herb-Drug Interaction Investigation. [PDF]

Biopharm Drug Dispos
Pharmacokinetic interactions between Echinacea and two antiviral drugs, favipiravir and atazanavir, were assessed in rats. The findings suggest that Echinacea does not significantly affect the pharmacokinetics of favipiravir and atazanavir. These results provide preliminary evidence that concurrent use of Echinacea with these antiviral drugs may be ...
Gajula SNR, Kallam JS, Kanukolanu A, Korada G, Nalla LV.   +4 more
europepmc   +2 more sources

Optimal Dose and Safety of Intravenous Favipiravir in Hospitalized Patients With COVID-19: A Dose-Escalating, Randomized Controlled Phase Ib Study. [PDF]

Clin Pharmacol Ther
AGILE (NCT04746183) is a Phase Ib/IIa platform, evaluating candidates to treat COVID‐19. Candidate Specific Trial 6 evaluated the safety and optimal dose of a novel intravenous formulation of favipiravir in a dose‐escalating, open‐label, randomized, controlled, Bayesian adaptive Phase Ib trial.
Rowland T, FitzGerald R, Challenger E, Dickinson L, Else LJ, Walker L, Hale C, Shaw V, Kelly C, Lyon R, Gibney J, Dhamani K, Irwin M, Enever Y, Tetlow M, Wood W, Reynolds H, Chiong J, Osanlou O, Pertinez H, Bullock K, Greenhalf W, Owen A, Lalloo DG, Jacobs M, Hiscox JA, Jaki T, Mozgunov P, Saunders G, Griffiths G, Khoo SH, Fletcher TE, AGILE CST‐6 Study Group.   +32 more
europepmc   +2 more sources

Favipiravir for treating COVID-19 [PDF]

, 2022
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To determine the efficacy and safety of favipiravir in patients with COVID-19 as compared to standard of care without ...
Alexander, H, Kirubakaran, R, Singh, B, Tharyan, P, Korula, P, Rupali, P, John, JS   +6 more
core   +1 more source

Favipiravir Tautomerism: A Short Theoretical Report [PDF]

, 2020
There is no experimental data about the tautomerism of Favipiravir (T-705). Therefore its tautomeric state was predicted by using density functional theory in gas phase and in solution (toluene, acetonitrile and water).
Liudmil, Antonov, Liudmil Antonov (8700597)   +1 more
core   +1 more source

A review of the safety of favipiravir – a potential treatment in the COVID-19 pandemic?

Journal of Virus Eradication, 2020
Background: Repurposing broad-spectrum antivirals is an immediate treatment opportunity for 2019 coronavirus disease (COVID-19). Favipiravir is an antiviral previously indicated for influenza and Ebola, which has shown some promise in early trials for ...
Victoria Pilkington, Toby Pepperrell, Andrew Hill   +2 more
doaj   +1 more source