Results 51 to 60 of about 59,983 (235)

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Favorite flavors of surfaces

Nature Immunology, 2005
Different peptide antigens induce T cell repertoires of very different diversity. An analysis of the effect on T cell receptor usage of re-engineering peptide features indicates that a lack of prominent side chains presented for recognition limits the T cell repertoire.
openaire   +3 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

Molecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda, Marina Reguero, Vanesa Abón, Marta Puyol   +3 more
wiley   +1 more source

Experts' Judgments of Management Journal Quality:An Identity Concerns Model [PDF]

, 2014
Many lists that purport to gauge the quality of journals in management and organization studies (MOS) are based on the judgments of experts in the field.
Aiken L. S., Ashkanasy N. M., Bauer D. J., Bensman S. J., Bezrukova K., Boyacigiller N., Bruner J. S., Byrne B. M., Cartter A. M., Clark T., Coe R., Cohen J., Cunningham G. B., Franke R. H., Gerard P. Hodgkinson, Glick W. H., Gomez-Mejia L. R., Haslam S. A., Hodgkinson G. P., Johnson J. L., Judge T. A., Kevin Daniels, Kim Peters, Lewis B., Lewis B. R., Link A. M., Lowe A., Messick D. M., Mingers J., Nunnally J. C., Oakes P. J., Oakes P. J., Orne M. T., Pendlebury D. A., Pfeffer J., Podsakoff P. M., Raudenbush S. W., Raudenbush S. W., S. Alexander Haslam, Saha S., Satorra A., Serenko A., Starbuck W. H., Tahai A., Tajfel H., Tajfel H., Turner J. C., Turner J. C., Whitley R., Yue W.   +49 more
core   +2 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Managerial Incentives and Favoritism in Promotion Decisions: Theory and Field Evidence [PDF]

This paper investigates the effects of managerial incentives on favoritism in promotion decisions. First, we theoretically show that favoritism leads to a lower quality of promotion decisions and in turn lower efforts.
Berger, Johannes, Herbertz, Claus, Sliwka, Dirk   +2 more
core  

Darwin’s Favorite Journal [PDF]

Cell, 2016
The Gardener’s Chronicle had been Darwin’s publication of choice, but beginning with a note on “The fertilization of winter-flowering plants” in Nature’s third issue (November 18, 1869), over the next ten years 41 out of 71 of Darwin’s publications appeared in Nature. Melinda Baldwin tells the story of Nature’s origin and its rise to prominence.
openaire   +3 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Exposing the Probabilistic Causal Structure of Discrimination [PDF]

, 2017
Discrimination discovery from data is an important task aiming at identifying patterns of illegal and unethical discriminatory activities against protected-by-law groups, e.g., ethnic minorities.
Bonchi, Francesco, Hajian, Sara, Mishra, Bud, Ramazzotti, Daniele   +3 more
core   +1 more source