Results 201 to 210 of about 2,166 (230)

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

Advanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu   +8 more
wiley   +1 more source

Epidemiology of Non-Contact Muscle Injuries in the Italian Male Elite Under-19 Football (Soccer) Championship. [PDF]

Sports Med Open
Magistrali M, Stefanini L, Abate M, Biancalana G, Stegagno A, Cugia P, Candoli P, Anania G, Lucchese PL, Gaddi D, Volpi P, Mariani F, Boldrini L, Filippi N, Cerrone A, Sirtori C, Battaglino P, Bravin G, Del Fabro E, Berti M, Vecchini E, Minetto MA.   +21 more
europepmc   +1 more source

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source

Effect of adaptive cruise control on fuel consumption in real-world driving conditions. [PDF]

Nat Commun
Moawad A, Zebiak M, Han J, Karbowski D, Zhang Y, Rousseau A.   +5 more
europepmc   +1 more source

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

Advanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li, Lan Wang, Zihao Zhang, Chunmei Qian, Ning Li, Wei Huang, Qian Ba, Xiaojian Liu, Mayu Sun   +8 more
wiley   +1 more source

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Cosmic Ionizing Radiation: A DNA Damaging Agent That May Underly Excess Cancer in Flight Crews. [PDF]

Int J Mol Sci
Toprani SM, Scheibler C, Mordukhovich I, McNeely E, Nagel ZD.   +4 more
europepmc   +1 more source

Differential disease tolerance mediates sex-biased illness severity in sepsis. [PDF]

Proc Natl Acad Sci U S A
Dobson B, Strayer K, Wijesinghe A, Schlechte J, Tejada O, Bartlett A, Stephens M, Changirwa D, Cho NA, Yu IL, Khan N, McDonald B.   +11 more
europepmc   +1 more source

Gaming expertise induces meso‑scale brain plasticity and efficiency mechanisms as revealed by whole-brain modeling. [PDF]

Neuroimage
Coronel-Oliveros C, Medel V, Orellana S, Rodiño J, Lehue F, Cruzat J, Tagliazucchi E, Brzezicka A, Orio P, Kowalczyk-Grębska N, Ibáñez A.   +10 more
europepmc   +1 more source

Editorial: How animals affect us: examining the influence of human-animal interactions on human's health. [PDF]

Front Vet Sci
Capela E Silva F, Kieson E, Stergiou AN, Pereira-Figueiredo I.   +3 more
europepmc   +1 more source