Results 101 to 110 of about 305,461 (343)

The Role of Fc Gamma Receptors in Broad Protection against Influenza Viruses

Vaccines, 2018
Recent studies have revealed multiple roles for Fc gamma receptors (FcγRs) in broad immunity against influenza viruses. Activating FcγR pathways can be harnessed to confer protection mediated by non-neutralizing anti-HA IgGs and to increase ...
Natalie K. Thulin, Taia T. Wang
doaj   +1 more source

Adhesion-induced phase separation of multiple species of membrane junctions

, 2002
A theory is presented for the membrane junction separation induced by the adhesion between two biomimetic membranes that contain two different types of anchored junctions (receptor/ligand complexes).
A. Albersdörfer, C.R.F. Monks, D. Zuckerman, D.M. Davis, G. Grakoui, G.I. Bell, Hsuan-Yi Chen, J. Nardi, N.J. Burroughs, R. Bruinsma, R. Bruinsma, R. Lipowsky, R.R. Netz, S. Komura, S.Y. Qi, T.R. Weikl, T.R. Weikl, T.R. Weikl, T.R. Weikl   +18 more
core   +1 more source

Substrate stiffness and VE-cadherin mechano-transduction coordinate to regulate endothelial monolayer integrity. [PDF]

, 2017
The vascular endothelium is subject to diverse mechanical cues that regulate vascular endothelial barrier function. In addition to rigidity sensing through integrin adhesions, mechanical perturbations such as changes in fluid shear stress can also ...
Andresen Eguiluz, Roberto C, Kaylan, Kerim B, Leckband, Deborah E, Underhill, Gregory H   +3 more
core   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Tumor intrinsic properties dictate Fc receptor expression and cancer cachexia associated increase in checkpoint inhibitor clearance

Frontiers in Immunology
PurposePatients with cancer cachexia display a general resistance to immune checkpoint inhibitor (ICI) therapy, and baseline ICI catabolic clearance is a predictive indicator for overall survival, independent of dose and drug exposure.
Bryan C. Remaily, Greg Young, Hannah Lathrop, Justin Thomas, Kyeongmin Kim, Trang T. Vu, Adeoluwa Adeluola, Camille Stanton, Gillian Mulcahy, Zhiliang Xie, Lauren Granchie, Yizhen Guo, Min Hai, Jessica Wedig, Maria Schmidt, Millennium Manna, Xiaokui Mo, Xiaokui Mo, Xiaokui Mo, Jeovanna Lowe, Jill A. Rafael-Fortney, Jill A. Rafael-Fortney, Edmund Folefac, Paul Gregorevic, Paul Gregorevic, Dwight H. Owen, Dwight H. Owen, Samuel K. Kulp, Latha P. Ganesan, Christopher C. Coss, Christopher C. Coss, Thomas A. Mace, Thomas A. Mace, Thomas A. Mace, Mitch A. Phelps, Mitch A. Phelps   +35 more
doaj   +1 more source

Rapid redistribution of clathrin onto macrophage plasma membranes in response to Fc receptor-ligand interaction during frustrated phagocytosis. [PDF]

, 1986
We have observed increases in assembled clathrin on the plasma membrane during "frustrated phagocytosis," the spreading of macrophages on immobilized immune complexes. Resident macrophages freshly harvested from the peritoneal cavity of mice and attached
Bainton, DF, Stenberg, PE, Takemura, R, Werb, Z   +3 more
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

PROTECTIVE ROLE OF ANTIBODIES IN TUBERCULOSIS AND HIV INFECTION

Медицина в Кузбассе, 2022
The review discusses the protective humoral mechanisms in tuberculosis and HIV infection. These include the immunoglobulin Fc receptor (Fc receptor) mediated antibody effector functions leading to pathogen clearance, antibody-dependent cellular ...
Нина Васильевна Мальцева
doaj  

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Tetraspanin–Fc receptor interactions

Platelets, 2005
The tetraspanins are a superfamily of membrane glycoproteins which facilitate the interaction of membrane and intracellular signalling molecules (e.g., integrins, pro-growth factors and their receptors, protein kinase-C) in the formation of membrane signalling microdomains (sometimes referred to as the tetraspanin web).
openaire   +2 more sources