Results 21 to 30 of about 173 (69)
South African Family Practice, 2018 The series, “Mastering your Fellowship”, provides examples of the question format encountered in the FCFP(SA) examination. The series aims to help family medicine registrars and their supervisors prepare for this examination.
Mergan Naidoo +3 more
doaj +9 more sources
Mastering your fellowship (Online)
South African Family Practice, 2017 The series, “Mastering your Fellowship”, provides examples of the question format encountered in the written examination, Part A of the FCFP (SA) examination. The series is aimed at helping family medicine registrars prepare for this examination.
Klaus B von Pressentin +2 more
doaj +9 more sources
Computer‐Aided Discovery of Potent Broad‐Spectrum Vaccine Adjuvants
Angewandte Chemie, Volume 135, Issue 18, April 24, 2023., 2023 New Au nanoparticle (AuNP) adjuvants are prepared through computer‐aided molecule design and machine learning to discover agonist ligands, and sulfur‐Au coordination chemistry guided well‐ordered presentation of ligands on AuNP surface. These AuNP adjuvants show advantages in multi‐toll like receptor (TLR) targeting and application as broad‐spectrum ...
Juan Ma +11 more
wiley +2 more sources
Paleoceanography and Paleoclimatology, Volume 38, Issue 9, September 2023., 2023 Abstract Quantifying variability in, and identifying the mechanisms behind, East Asian dust production and transport across the last several million years is essential for constraining future dust emissions and deposition. Our current understanding of East Asian dust dynamics through the Quaternary is primarily limited to low‐resolution records from ...
Jordan T. Abell +9 more
wiley +1 more source
Stem Cells International, Volume 2023, Issue 1, 2023., 2023 Large numbers of Calpain 3 (CAPN3) mutations cause recessive forms of limb‐girdle muscular dystrophy (LGMD2A/LGMDR1) with selective atrophy of the proximal limb muscles. We have generated induced pluripotent stem cells (iPSC) from a patient with two mutations in exon 3 and exon 4 at the calpain 3 locus (W130C, 550delA).
Lampros Mavrommatis +10 more
wiley +1 more source
Plant, Cell &Environment, Volume 45, Issue 10, Page 3157-3170, October 2022., 2022 Abstract Plant root absorbs water and nutrients from the soil, and the root apoplastic fluid (AF) is an important intermediate between cells and the surrounding environment. The acid growth theory suggests that an acidic AF is needed for cell wall expansion during root growth.
Quang Tran +5 more
wiley +1 more source
Residency time of agonists does not affect the stability of GPCR–arrestin complexes
British Journal of Pharmacology, Volume 179, Issue 16, Page 4107-4116, August 2022., 2022 Background and Purpose The interaction of arrestins with G‐protein coupled receptors (GPCRs) desensitizes agonist‐dependent receptor responses and often leads to receptor internalization. GPCRs that internalize without arrestin have been classified as “class A” GPCRs whereas “class B” GPCRs co‐internalize with arrestin into endosomes.
Nadja Mösslein +4 more
wiley +1 more source
Identification of a STIM1 Splicing Variant that Promotes Glioblastoma Growth
Advanced Science, Volume 9, Issue 11, April 14, 2022., 2022 The authors report a novel splice variant of stromal interaction molecule 1, designated STIM1β, that is abnormally upregulated in glioma cells. A 31‐residue insertion in the cytosolic domain of STIM1β renders itself prone for activation, thereby perturbing Ca2+ homeostasis and promoting glioblastoma growth.
Jiansheng Xie +22 more
wiley +1 more source
International Journal of Clinical Practice, Volume 75, Issue 8, August 2021., 2021 Abstract Aims Opioid misuse and overuse have contributed to a widespread overdose crisis and many patients and physicians are considering medical cannabis to support opioid tapering and chronic pain control. Using a five‐step modified Delphi process, we aimed to develop consensus‐based recommendations on: 1) when and how to safely initiate and titrate ...
Aaron Sihota +22 more
wiley +1 more source
South African Family Practice, 2015 The new series, “Mastering your Fellowship”, will provide examples of the question format encountered in the written examination, Part I of the FCFP(SA) examination.
Klaus B. von Pressentin, Bob Mash
doaj +5 more sources