Results 181 to 190 of about 52,959 (244)

Effects of POPG and Cholesterol on Freeze–Thawing Mediated Content Exchange and Transcription in Giant Unilamellar Vesicles

ChemBioChem, Volume 27, Issue 21, 12 November 2026.
Phospholipid 1‐palmitoyl‐2‐oleoyl‐sn‐glycero‐3‐phospho‐(1′‐rac‐glycerol)/cholesterol membranes suppress transcription in intact giant unilamellar vesicles but show the highest RNA synthesis following freeze–thaw (F/T)‐mediated content mixing. These findings highlight the context‐dependent effects of membrane composition on biochemical activity ...
Tsubasa Yamashina, Masaya Oki, Gakushi Tsuji   +2 more
wiley   +1 more source

FCM-Encoder: a novel interpretable framework with vision-language reasoning for coronary artery disease and solitary pulmonary nodule classification. [PDF]

BMC Med Inform Decis Mak
Feleki A, Papageorgiou E, Apostolopoulos ID, Apostolopoulos DJ, Papathanasiou N, Papandrianos NI.   +5 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, Volume 20, Issue 11, Page 2839-2859, November 2026.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Liver-specific amino acid metabolism impacts on efficacy of cancer immunotherapy. [PDF]

Oncogene
Fukumoto Y, Mukohara F, Iwatsuru M, Ueda Y, Kanzaki H, Ogasawara S, Lin J, Kawazu M, Ninomiya T, Kemmotsu N, Nagasaki J, Toyooka S, Osawa T, Ishino T, Togashi Y.   +14 more
europepmc   +1 more source

Poly(Alkoxythiophene) Rod‐Coil Block Copolymers for Organic Electrochemical Transistors

Advanced Materials, Volume 38, Issue 61, 2 November 2026.
We present the first synthesis of poly(3‐alkoxythiophene) rod‐coil block copolymers as a new architecture for OMIECs. Incorporating PEG and PLLA coils can enhance device performance beyond the homopolymer. The figure‐of‐merit depends uniquely on coil length.
Junfu Tian, Wentao Shan, Rachael Found, Paola Mantegazza, Francesco Leoni, Andreas W. Erhardt, Yuyun Yao, Matus Stredansky, Arianna Magni, Adam Marks, Elena Chulanova, Zeinab Hamid, Yueying Huang, Wanpeng Lu, Xian'e Li, Baopu Zhang, Qingpei Wan, Christina Kousseff, Matilde Concilio, Ruth Theresia Arwani, Caroline A. Ross, Sahika Inal, Giovanni Costantini, Iain McCulloch   +23 more
wiley   +1 more source

Intravenous Iron Therapy in Heart Failure With Iron Deficiency: An Umbrella Review of Systematic Reviews and Meta-Analyses. [PDF]

Cureus
Kshatri AHS, Arif S, Yousaf S, Habib M, Saif M, Mushtaq MM.   +5 more
europepmc   +1 more source

PROTAC‐Engineered Protein/DNA Nanoantigen is a Potent Booster for Dendritic Cell Vaccines in Cancer Immunotherapy

Advanced Science, Volume 13, Issue 61, 3 November 2026.
A PROTAC‐functionalized protein/DNA‐integrated nanoantigen platform is developed to enhance dendritic cell vaccine potency. By combining a VHL‐recruiting peptide‐modified antigen with a sustained expression plasmid within CaCO3 nanoparticles, this system amplifies cross‐presentation, promotes DC maturation, and elicits robust Th1 and CTL responses ...
Peng Liu, Qiang Chen, Zhe Zhou, Yuekang Xu, Jinyao Li   +4 more
wiley   +1 more source

A bone to pick with ferric carboxymaltose. [PDF]

Blood
Finberg KE, Auerbach M.
europepmc   +1 more source

Contrasting Spatial Genomic Structure in Two Widespread Grassland Species Across Norway Supports Species‐Specific Seed Sourcing

Ecology and Evolution, Volume 16, Issue 11, November 2026.
Seed sourcing for ecological restoration often relies on broad administrative zones that may not reflect underlying genetic structure. Using genome‐wide ddRAD‐seq data from two co‐occurring Norwegian grassland species, we show contrasting patterns: Silene dioica exhibits moderate spatial genetic structure indicating the need for localized sourcing ...
Abel Gizaw, Hans Martin Hanslin, Trygve S. Aamlid, Håkon Borch, Hana Šípková, Carl Gunnar Fossdal   +5 more
wiley   +1 more source

Real‐World Survival Outcomes of Venetoclax Combination Therapies in Acute Myeloid Leukemia: Impact of Minimal Residual Disease Status and Antifungal Prophylaxis

Hematological Oncology, Volume 44, Issue 6, November 2026.
ABSTRACT In recent years the addition of the oral BCL2 inhibitor venetoclax to hypomethylating agents (HMAs) has emerged as the standard‐of‐care for patients with acute myeloid leukemia (AML) who are not fit for intensive chemotherapy, significantly improving survival and quality‐of‐life.
Mariarita Sciumè, Alessandro Bosi, Alfredo Marchetti, Fabio Serpenti, Pasquale De Roberto, Sonia Fabris, Francesco Versino, Elena Tagliaferri, Francesco Passamonti, Nicola Stefano Fracchiolla   +9 more
wiley   +1 more source