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IL6 suppresses vaccine responses in neonates by enhancing IL2 activity on T follicular helper cells
The inability of neonates to develop CD4+FoxP3-CXCR5hiPD-1hi T follicular helper (TFH) cells contributes to their weak vaccine responses. In previous studies, we measured diminished IgG responses when IL-6 was co-injected with a pneumococcal conjugate ...
Swetha Parvathaneni+5 more
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Background The Bacillus cereus group, also known as B. cereus sensu lato (s.l.) contains ubiquitous spore-forming bacteria found in the environment including strains from the B. cereus sensu stricto (s.s.) species. They occur naturally in a wide range of
Nadine Yossa+5 more
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qPCR detection of viable Bacillus cereus group cells in cosmetic products
Reference methods for microbiological safety assessments of cosmetics rely on culture methods that reveal colonies of live microorganisms on growth media. Rapid molecular technologies, such as qPCR, detects the presence of target DNA in samples from dead
Nadine Yossa+8 more
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Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent chronic liver disease, and patient susceptibility to its onset and progression is influenced by several factors.
Volodymyr P. Tryndyak+6 more
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COVID-19 – Therapeutic controversies. The case of ibuprofen [PDF]
Shortly after the declaration of the SARS-CoV-2 infection pandemic by the World Health Organization (WHO), a controversy erupted over the worsening of the disease by NSAIDs, particularly ibuprofen.
Camil-Eugen Vari+3 more
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A Review of FDA-Approved Antiparasitic Drugs in USA for Sheep and Goats: Their Synthesis and Pharmaceutical Use [PDF]
This review describes the Food and Drug Administration (FDA)-approved antiparasitic drugs for sheep and goats in the USA updated to 2021. The emerging drug resistance is posing a significant burden for the treatment of parasitic infections in these small
Davide Benedetto Tiz, Črtomir Podlipnik
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Preventing the spread of infectious disease relies heavily upon the development and implementation of public health interventions. The requisite debate over the effectiveness of these interventions is accompanied by discussions about which, if any ...
Girvin Liggans+9 more
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Background Reference genes are often interchangeably called housekeeping genes due to 1) the essential cellular functions their proteins provide and 2) their constitutive expression across a range of normal and pathophysiological conditions.
Lai Xu+11 more
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Blockchain in Healthcare Today Best Article Award 2020
The award was announced during the ConV2X 2021 conference, themed “Blueprint for a New Digital Health Era,” broadcast November 9-11, 2021. The winning article is titled: "The Last Mile: DSCSA Solution Through Blockchain Technology: Drug Tracking, Tracing,
Tory Cenaj, Founder and Publisher, Partners in Digital Health, Presenter+1 more
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SARS-CoV2 infection has been linked to a wide range of clinical severities and the immunopathology is still under intense scrutiny. Here, the authors uncover an association of antibody affinity maturation and plasma IgA levels with clinical outcome in ...
Juanjie Tang+8 more
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