Results 101 to 110 of about 812,951 (357)
ALS plasma biomarkers reveal neurofilament and pTau correlate with disease onset and progression
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective We performed a pilot screen to assess the utility of the NULISA™ (Nucleic‐acid‐Linked Immuno‐Sandwich Assay) platform in the identification of amyotrophic lateral sclerosis (ALS) biomarkers. Methods Plasma from 86 individuals (48 ALS, 18 asymptomatic C9orf72 repeat expansion carriers (AsymC9), and 20 healthy controls) was analyzed ...
Eleanor V. Thomas +10 more
wiley +1 more source
Lie derivatives along antisymmetric tensors, and the M-theory superalgebra [PDF]
arXiv, 2005 Free differential algebras (FDA's) provide an algebraic setting for field theories with antisymmetric tensors. The "presentation" of FDA's generalizes the Cartan-Maurer equations of ordinary Lie algebras, by incorporating p-form potentials. An extended Lie derivative along antisymmetric tensor fields can be defined, and used to recover a Lie algebra ...
arxiv
Opportunities for Improving the Drug Development Process: Results from a Survey of Industry and the FDA [PDF]
In the United States, the Food and Drug Administration (FDA) agency is responsible for regulating the safety and efficacy of biopharmaceutical drug products. Furthermore, the FDA is tasked with speeding new medical innovations to market.
Adrian H. B. Gottschalk +2 more
core
Capturing what matters: Patient‐reported LGI1‐ANTibody encephalitis outcome RatiNg scale (LANTERN)
Annals of Clinical and Translational Neurology, EarlyView.Abstract Background LGI1‐antibody encephalitis (LGI1‐Ab‐E) is a common form of autoimmune encephalitis where most patients demonstrate ‘good’ clinician‐rated outcomes. However, more targeted questionnaires reveal numerous debilitating symptoms for many years.
Mark J Kelly +9 more
wiley +1 more source
FDA: Feature Disruptive Attack [PDF]
arXiv, 2019 Though Deep Neural Networks (DNN) show excellent performance across various computer vision tasks, several works show their vulnerability to adversarial samples, i.e., image samples with imperceptible noise engineered to manipulate the network's prediction.
arxiv
Current Directions in Biomedical Engineering, 2016 The kink behavior of vascular stents is of particular interest for clinicians, stent manufacturers and regulatory as a kinked stent generates a lumen loss in the stented vessel and can lead to in-stent restenosis.
Brandt-Wunderlich Christoph +5 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective We aimed to assess differences in baseline characteristics, efficacy, and safety of advanced therapies between male and female patients with axial spondyloarthritis (axSpA) in randomized controlled trials (RCTs). Methods We conducted a systematic literature search for RCTs assessing the efficacy of advanced therapies in patients with axSpA ...
Angel Gao +5 more
wiley +1 more source
CYBERSECURITY OF MEDICAL SYSTEMS: CHALLENGES AND SOLUTIONS IN THE CONTEXT OF THE INTERNET OF THINGS
Радіоелектронні і комп'ютерні системи, 2017 This article reviews the main challenges and solutions in the field of cybersecurity medical systems in the context of the Internet of things. The authors identified key vulnerabilities, threats and risks of health care network devices.
Анастасія Андріївна Стрєлкина +1 more
doaj +1 more source
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Transarterial Chemoembolization (TACE) may aggravate liver fibrosis. In this study, a novel oral targeting nanoemulsion is fabricated to enhance the therapeutic effect of antifibrotic drug‐pirfenidone (PFD) on fibrosis after TACE. Studies have shown that PFD nanoemulsion can enhance the oral liver targeting effect of PFD, and effectively improve the ...
Zhimei Cheng +12 more
wiley +1 more source