Results 121 to 130 of about 812,951 (357)

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

open access: yesAdvanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan   +4 more
wiley   +1 more source

Effects of Crude Oil, Dispersant, and Oil-Dispersant Mixtures on Human Fecal Microbiota in an In Vitro Culture System

open access: yesmBio, 2012
The Deepwater Horizon oil spill of 2010 raised concerns that dispersant and dispersed oil, as well as crude oil itself, could contaminate shellfish and seafood habitats with hazardous residues that had potential implications for human health and the ...
Jong Nam Kim   +3 more
doaj   +1 more source

Undue Process at the FDA [PDF]

open access: yes, 2013
For over 40 years, the Food and Drug Administration has been collecting evidence that the routine administration of antibiotics to animals destined for the food supply contributes to the development of antibiotic-resistant infections in the human ...
Heinzerling, Lisa
core   +1 more source

Stable, Easy‐to‐Handle, Fully Autologous Electrospun Polymer‐Peptide Skin Equivalent for Severe Burn Injuries

open access: yesAdvanced Functional Materials, EarlyView.
A bioengineered skin equivalent composed of electrospun poly(ε‐caprolactone) (PCL) and the bioactive peptide Fmoc‐FRGD is developed for severe burn treatment. This scaffold promotes full‐thickness skin regeneration by supporting cellular adhesion and integration. In‐vitro and in‐vivo studies show enhanced mechanical stability, accelerated wound closure,
Dana Cohen‐Gerassi   +11 more
wiley   +1 more source

Monoclonal antibodies targeting sites in respiratory syncytial virus attachment G protein provide protection against RSV-A and RSV-B in mice

open access: yesNature Communications
Currently, only Palivizumab and Nirsevimab that target the respiratory syncytical virus (RSV) fusion protein are licensed for pre-treatment of infants. Glycoprotein-targeting antibodies may also provide protection against RSV.
Youri Lee   +5 more
doaj   +1 more source

Probiotic‐Based Mineralized Living Materials to Produce Antimicrobial Yogurts

open access: yesAdvanced Healthcare Materials, EarlyView.
The self‐assembly and mineralization of collagen in the presence of probiotics produces hybrid living materials that hosts and protects the cells. Intra‐ and interfibrillar mineralization of collagen fibers, as occurring in bone, results, respectively, in a bulk and single‐cell protective layer of cells, that survive in simulated gastric conditions and,
Gloria B. Ramírez‐Rodríguez   +5 more
wiley   +1 more source

Discrete vs. functional based data to analyze countermovement jump performance [PDF]

open access: yes, 2012
While discrete point analysis (DPA) (e.g. peak power) is by far the most common method of analyzing movement data, it may have significant limitations because it ignores the vast majority of a signal’s data.
Moran, Kieran   +2 more
core  

Radiation‐Resistant Bacteria Deinococcus radiodurans‐Derived Extracellular Vesicles as Potential Radioprotectors

open access: yesAdvanced Healthcare Materials, EarlyView.
Deinococcus radiodurans‐derived extracellular vesicles (R1‐EVs) provide radioprotection against total‐body irradiation‐induced acute radiation syndrome in mice. R1‐EVs mitigate oxidative damage by scavenging free radicals, promoting intestinal repair, enhancing hematopoietic function, and modulating immune responses. This study highlights the potential
Jeong Moo Han   +7 more
wiley   +1 more source

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