Results 131 to 140 of about 1,036,661 (382)

The Coming of Age of AI/ML in Drug Discovery, Development, Clinical Testing, and Manufacturing: The FDA Perspectives

open access: yesDrug Design, Development and Therapy, 2023
Sarfaraz K Niazi College of Pharmacy, University of Illinois, Chicago, IL, USACorrespondence: Sarfaraz K Niazi, Tel +1-312-297-0000, Email niazi@niazi.comAbstract: Artificial intelligence (AI) and machine learning (ML) represent significant advancements ...
Niazi SK
doaj  

Host‐Guest Inclusion Chemistry From Supramolecular Architecture Enabling Anti‐Biofouling Surfaces for Oesophagus Stents

open access: yesAdvanced Functional Materials, EarlyView.
A slippery coating with exceptional anti‐biofouling performance is developed using biocompatible materials for oesophagus stents. Host‐guest inclusion complex formation capabilities of FDA‐approved supramolecules, cyclodextrins are exploited, which significantly enhances the stability of the surface.
Jianhui Zhang   +7 more
wiley   +1 more source

Process development for production of non-originator NISTmAb from CHO and NS0 cell lines

open access: yesmAbs
Cell lines that produce non-originator versions of the National Institute of Standards and Technology (NIST) monoclonal antibody reference material 8671 (NISTmAb) are invaluable to the biopharmaceutical industry because, unlike typical commercial cell ...
Erica J. Fratz-Berilla   +4 more
doaj   +1 more source

Curvatures and potential of M-theory in D=4 with fluxes and twist

open access: yes, 2005
We give the curvatures of the free differential algebra (FDA) of M--theory compactified to D=4 on a twisted seven--torus with the 4--form flux switched on. Two formulations are given, depending on whether the 1--form field strengths of the scalar fields (
A. Tomasiello   +22 more
core   +1 more source

A Bioengineered Model of the Human Cornea for Preclinical Assessment of Human Ocular Exposure to Environmental Toxicants

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This paper presents a microphysiological system containing an array of individually addressable living corneal tissues constructed using primary human cells. The bioengineered eye model can simulate acute exposure of the human cornea to different types of environmental toxicants and provides a novel platform for visualization and quantitative ...
Se‐jeong Kim   +12 more
wiley   +1 more source

D=4, N=2 Supergravity in the Presence of Vector-Tensor Multiplets and the Role of higher p-forms in the Framework of Free Differential Algebras

open access: yes, 2007
We thoroughly analyze at the bosonic level, in the framework of Free Differential Algebras (FDA), the role of 2-form potentials setting in particular evidence the precise geometric formulation of the anti-Higgs mechanism giving mass to the tensors.
Andrianopoli, Laura   +2 more
core  

Bioprinted Micro‐Clots for Kinetic Analysis of Endothelial Cell‐Mediated Fibrinolysis

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This paper describes the development of a microscale model that quantifies the breakdown of fibrin by endothelial cells. The small size scale of this engineered system enables fibrin breakdown to be observed without the addition of external activators. This system could help in identifying compounds which both promote and hinder thrombosis.
Jonathan J. Chang   +5 more
wiley   +1 more source

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